ZFIN ID: ZDB-GENE-050208-507
Gene Name: CACN subunit beta associated regulatory protein b
Gene Symbol: cbarpb    Nomenclature History

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Previous Names: dos, dosb, si:dkey-28h18.4 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have ion channel binding activity. Predicted to be involved in negative regulation of calcium ion-dependent exocytosis and negative regulation of voltage-gated calcium channel activity. Predicted to colocalize with secretory granule. Orthologous to human CBARP (CACN subunit beta associated regulatory protein).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000071325 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 7 figures (18 images) from Thisse et al., 2005 [eu438]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16941 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cbarpb HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cbarpb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process negative regulation of voltage-gated calcium channel activity (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ion channel binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cbarpb-202 (1)    Ensembl 1749
    cbarpb-203 (1)    Ensembl 1144
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cbarpb No data available
    MARKER RELATIONSHIPS
    cbarpb Contained in: [BAC] DKEY-28H18 (1) (order this)
    cbarpb Encodes: [EST] eu438 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    Genomic GenBank:BX664631 (1) 220242 nt Blast at MegaBLAST
    Polypeptide UniProtKB:F1R6L5 (1) 762 aa
    Sequence Information (all 7)
    ORTHOLOGY for cbarpb ( Chr: 22 )
    CITATIONS (17)