Gene
mrasb
- ID
- ZDB-GENE-050208-495
- Name
- muscle RAS oncogene homolog b
- Symbol
- mrasb Nomenclature History
- Previous Names
-
- mras
- si:rp71-1n18.3
- Type
- protein_coding_gene
- Location
- Chr: 22 Mapping Details/Browsers
- Description
- Predicted to enable GDP binding activity; GTP binding activity; and GTPase activity. Predicted to be active in plasma membrane. Human ortholog(s) of this gene implicated in Noonan syndrome 11. Orthologous to human MRAS (muscle RAS oncogene homolog).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Noonan syndrome 11 | Alliance | Noonan syndrome 11 | 618499 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | P-loop containing nucleoside triphosphate hydrolase | Small GTPase | Small GTPase, Ras-type | Small GTP-binding domain |
|---|---|---|---|---|---|---|
| UniProtKB:A0A286Y9A7 | InterPro | 209 |
Interactions and Pathways
No data available
Plasmids
No data available