Gene

bap1

ID
ZDB-GENE-050208-492
Name
BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase)
Symbol
bap1 Nomenclature History
Previous Names
  • si:dkey-42i9.9
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to have chromatin binding activity and thiol-dependent ubiquitin-specific protease activity. Involved in Notch signaling pathway and cranial skeletal system development. Predicted to localize to PR-DUB complex and cytoplasm. Human ortholog(s) of this gene implicated in basal cell carcinoma. Orthologous to human BAP1 (BRCA1 associated protein 1).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With bap1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Tumor predisposition syndrome 614327
Associated With bap1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001578 Peptidase C12, ubiquitin carboxyl-terminal hydrolase
Domain IPR041507 Peptidase C12, C-terminal domain
Homologous_superfamily IPR036959 Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily
Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
Domain Details Per Protein
Protein Length Papain-like cysteine peptidase superfamily Peptidase C12, C-terminal domain Peptidase C12, ubiquitin carboxyl-terminal hydrolase Peptidase C12, ubiquitin carboxyl-terminal hydrolase superfamily
UniProtKB:A1L2G3 755
UniProtKB:F1QJ12 755
UniProtKB:A0A2R8Q190 756
UniProtKB:Q0P440 274
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations