Gene
dchs1b
- ID
- ZDB-GENE-050208-41
- Name
- dachsous cadherin-related 1b
- Symbol
- dchs1b Nomenclature History
- Previous Names
-
- dchs1
- im:7136458 (1)
- im:7156059
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Description
- Predicted to have calcium ion binding activity. Involved in several processes, including atrioventricular canal development; cortical granule exocytosis; and mitotic cleavage furrow formation. Predicted to localize to integral component of membrane and plasma membrane. Human ortholog(s) of this gene implicated in Van Maldergem syndrome 1 and mitral valve prolapse. Is expressed in several structures, including blastomere; heart; mesoderm; musculature system; and retina. Orthologous to human DCHS1 (dachsous cadherin-related 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 13 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:7136458 (9 images)
- IMAGE:7156059 (9 images)
Wild Type Expression Summary
- All Phenotype Data
- 10 figures from 3 publications
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mitral valve prolapse | Alliance | Mitral valve prolapse 2 | 607829 |
| Van Maldergem syndrome 1 | Alliance | Van Maldergem syndrome 1 | 601390 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Cadherin conserved site | Cadherin-like | Cadherin-like superfamily |
|---|---|---|---|---|
|
UniProtKB:F1QXA3
|
921 | |||
|
UniProtKB:Q5CZT3
|
436 | |||
|
UniProtKB:E9QEN9
|
274 | |||
|
UniProtKB:F1QGX1
|
3298 |
| Type | Name | Length (nt) | Analysis |
|---|---|---|---|
| mRNA |
dchs1b-201
(1)
|
2170 nt | |
| mRNA |
dchs1b-203
(1)
|
4224 nt |
Interactions and Pathways
No data available
Plasmids
No data available