ZFIN ID: ZDB-GENE-050208-393
Gene Name: PX domain containing serine/threonine kinase
Gene Symbol: pxk    Nomenclature History

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Previous Names: sb:eu550, si:dkeyp-87e7.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have actin binding activity; anion binding activity; and protein kinase activity. Predicted to be involved in negative regulation of ATPase activity; negative regulation of ion transport; and regulation of membrane potential. Predicted to localize to cytoplasm and plasma membrane. Orthologous to human PXK (PX domain containing serine/threonine kinase like).
Genome Resources: Alliance (1),  Gene:557065 (1),  Ensembl(GRCz11):ENSDARG00000063195 (2)
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu550]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa16786 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32380 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pxk HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH pxk VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process protein phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function actin binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pxk-201 (1)    Ensembl 4698
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pxk No data available
    MARKER RELATIONSHIPS
    pxk Contained in: [BAC] DKEYP-87E7 (1)
    pxk Encodes: [EST] eu550 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001082808 (1) 4698 nt
    Genomic GenBank:BX649457 (1) 159207 nt
    Select Tool
    Polypeptide UniProtKB:Q1LVS2 (1) 575 aa
    Sequence Information (all 16)
    ORTHOLOGY for pxk ( Chr: 22 )
    CITATIONS (19)