Gene

slx4

ID
ZDB-GENE-050208-359
Name
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
Symbol
slx4 Nomenclature History
Previous Names
  • btbd12
  • fancp (1)
  • si:dkey-44g23.4
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to contribute to 3'-flap endonuclease activity; 5'-flap endonuclease activity; and crossover junction endodeoxyribonuclease activity. Involved in gall bladder development and hepatic duct development. Predicted to localize to Slx1-Slx4 complex. Human ortholog(s) of this gene implicated in Fanconi anemia complementation group P. Orthologous to human SLX4 (SLX4 structure-specific endonuclease subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
7 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slx4 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Fanconi anemia, complementation group P 613951
Associated With slx4 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000210 BTB/POZ domain
Domain IPR013087 Zinc finger C2H2-type
Family IPR018574 Structure-specific endonuclease subunit Slx4
Homologous_superfamily IPR011333 SKP1/BTB/POZ domain superfamily
Domain Details Per Protein
Protein Length BTB/POZ domain SKP1/BTB/POZ domain superfamily Structure-specific endonuclease subunit Slx4 Zinc finger C2H2-type
UniProtKB:F1QPU2 1719
UniProtKB:A0A8M1RN23 1720
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA slx4-201 (1) Ensembl 5452 nt
mRNA slx4-202 (1) Havana 623 nt
mRNA slx4-203 (1) Ensembl 5431 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Citations