Gene

pip5k1ca

ID

ZDB-GENE-050208-358

Name

phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a

Symbol

pip5k1ca Nomenclature History

Previous Names

pip5k1c (1)
si:ch211-197g15.13 (1)
si:dkey-29i9.1 (1)

Type

protein_coding_gene

Location

Chr: 22 Mapping Details/Browsers

Description

Predicted to have ATP binding activity and phosphatidylinositol phosphate kinase activity. Predicted to be involved in phosphatidylinositol metabolic process and phosphorylation. Is expressed in head and pronephric duct. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Orthologous to human PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma).

Genome Resources

Note

None

Expression

All Expression Data

1 figure from Xu et al., 2018

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Xu et al., 2018
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With pip5k1ca Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Lethal congenital contractural syndrome 3	611369

Associated With pip5k1ca Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR002498	Phosphatidylinositol-4-phosphate 5-kinase, core
Family	IPR023610	Phosphatidylinositol-4-phosphate 5-kinase
Homologous_superfamily	IPR027483	Phosphatidylinositol-4-phosphate 5-kinase, C-terminal
Homologous_superfamily	IPR027484	Phosphatidylinositol-4-phosphate 5-kinase, N-terminal

Domain Details Per Protein

Protein	Length	Phosphatidylinositol-4-phosphate 5-kinase	Phosphatidylinositol-4-phosphate 5-kinase, core	Phosphatidylinositol-4-phosphate 5-kinase, C-terminal	Phosphatidylinositol-4-phosphate 5-kinase, N-terminal
UniProtKB:E7F4U5 InterPro	682
UniProtKB:A0A2R8RYD9 InterPro	577
UniProtKB:Q1LVG1 InterPro	376
UniProtKB:A8KB45 InterPro	274
UniProtKB:A0A2R8QSH8 InterPro	672
UniProtKB:A0A2R8QI07 InterPro	652
UniProtKB:A0A2R8Q455 InterPro	639

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Length (nt)	Analysis
mRNA	pip5k1ca-201 (1) Ensembl	2558 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Gene Tree: Ensembl

Citations