ZFIN ID: ZDB-GENE-050208-358
Gene Name: phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a
Gene Symbol: pip5k1ca    Nomenclature History

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Previous Names: pip5k1c (1), si:ch211-197g15.13 (1), si:dkey-29i9.1 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and phosphatidylinositol phosphate kinase activity. Predicted to be involved in phosphatidylinositol metabolic process and phosphorylation. Is expressed in head and pronephric duct. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Orthologous to human PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma).
Genome Resources: Alliance (1),  Gene:798876 (1),  Ensembl(GRCz11):ENSDARG00000076001 (2)
GENE EXPRESSION
All Expression Data: Fig. 2 from Xu et al., 2018
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa3152 Point Mutation Unknown Premature Stop ENU
sa24142 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45766 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-pip5k1ca N/A 1
    DISEASE ASSOCIATED WITH pip5k1ca HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Lethal congenital contractural syndrome 3 611369
    DISEASE ASSOCIATED WITH pip5k1ca VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphatidylinositol metabolic process (more)
    Molecular Function ATP binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA pip5k1ca-201 (1)    Ensembl 2558
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pip5k1ca No data available
    MARKER RELATIONSHIPS
    pip5k1ca Contained in: [BAC] CH73-243B8 (1), CH211-197G15 (1), DKEY-29I9 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_002666250 (1) 4830 nt
    Genomic GenBank:BX649327 (1) 206348 nt Blast at MegaBLAST
    Polypeptide UniProtKB:E7F4U5 (1) 682 aa
    Sequence Information (all 26)
    ORTHOLOGY for pip5k1ca ( Chr: 22 )
    CITATIONS (18)