| ZFIN ID: ZDB-GENE-050208-358 |
| Gene Name: | phosphatidylinositol-4-phosphate 5-kinase, type I, gamma a | |||||||||||||
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| Gene Symbol: | pip5k1ca Nomenclature History |
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Attributions
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| Previous Names: | pip5k1c (1), si:ch211-197g15.13 (1), si:dkey-29i9.1 (1) | |||||||||||||
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| Gene Type: | protein_coding_gene | |||||||||||||
| Location: | Chr: 22 Mapping Details/Browsers | |||||||||||||
| Description: | Predicted to have ATP binding activity and phosphatidylinositol phosphate kinase activity. Predicted to be involved in phosphatidylinositol metabolic process and phosphorylation. Is expressed in head and pronephric duct. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Orthologous to human PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma). | |||||||||||||
| Genome Resources: | Alliance (1), Gene:798876 (1), Ensembl(GRCz11):ENSDARG00000076001 (2) | |||||||||||||
| All Expression Data: | Fig. 2 from Xu et al., 2018 |
| Wild-type Stages, Structures: | Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h) |
MUTATIONS AND SEQUENCE TARGETING REAGENTS
| Allele | Type | Localization | Consequence | Mutagen | Suppliers |
|---|---|---|---|---|---|
| sa3152 | Point Mutation | Unknown | Premature Stop | ENU | |
| sa24142 | Point Mutation | Unknown | Premature Stop | ENU |
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| sa45766 | Point Mutation | Unknown | Premature Stop | ENU |
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Sequence Targeting Reagents
| Targeting Reagent | Created Alleles | Publications |
|---|---|---|
| MO1-pip5k1ca | N/A | 1 |
PHENOTYPE
| Data: | 4 figures from Xu et al., 2018 |
| Observed in: |
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Lethal congenital contractural syndrome 3 | 611369 |
GENE ONTOLOGY
| Ontology | GO Term |
|---|---|
| Biological Process | phosphatidylinositol metabolic process (more) |
| Molecular Function | ATP binding (more) |
| Type | Name | Length (nt) | Analysis | |
|---|---|---|---|---|
| mRNA |
pip5k1ca-201
(1)
|
2558 |
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| Browsers: NCBI, Ensembl, ZFIN |
INTERACTIONS AND PATHWAYS
ANTIBODIES
No data available
PLASMIDS
No data available
CONSTRUCTS WITH SEQUENCES FROM pip5k1ca
No data available
MARKER RELATIONSHIPS
| pip5k1ca Contained in: | [BAC] CH73-243B8 (1), CH211-197G15 (1), DKEY-29I9 (1) (order this) |
SEQUENCE INFORMATION
| Type | Accession # | Length (nt/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:XM_002666250 (1) | 4830 nt |
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| Genomic | GenBank:BX649327 (1) | 206348 nt | Blast at MegaBLAST |
| Polypeptide | UniProtKB:E7F4U5 (1) | 682 aa |
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ORTHOLOGY for pip5k1ca (
Chr:
22
)
CITATIONS (18)