ZFIN ID: ZDB-GENE-050208-336
Gene Name: cathepsin 12
Gene Symbol: cts12    Nomenclature History

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Previous Names: ctskl (1), si:dkey-121a11.6

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 22 Mapping Details/Browsers
Description: Predicted to have cysteine-type endopeptidase activity. Predicted to be involved in proteolysis involved in cellular protein catabolic process. Predicted to localize to the extracellular space and lysosome.
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000042753 (1)
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1007 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12959 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cts12 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH cts12 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component extracellular space (more)
    Molecular Function cysteine-type peptidase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Active_site IPR000169 Cysteine peptidase, cysteine active site
    Domain IPR000668 Peptidase C1A, papain C-terminal
    Domain IPR013201 Cathepsin propeptide inhibitor domain (I29)
    Active_site IPR025660 Cysteine peptidase, histidine active site
    Active_site IPR025661 Cysteine peptidase, asparagine active site
    Homologous_superfamily IPR038765 Papain-like cysteine peptidase superfamily
    Domain IPR039417 Papain-like cysteine endopeptidase
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA cts12-202 (1)    Ensembl 859
    ncRNA cts12-002 (1) 769
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cts12 No data available
    MARKER RELATIONSHIPS
    cts12 Contained in: [BAC] DKEY-121A11 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    Genomic GenBank:BX465190 (1) 183103 bp
    Select Tool
    Polypeptide UniProtKB:F1QCP8 (1) 349 aa
    Sequence Information (all 5)
    ORTHOLOGY for cts12 ( Chr: 22 )
    CITATIONS (17)