ZFIN ID: ZDB-GENE-050208-221
Gene Name: aggrecan a
Gene Symbol: acana
Previous Names: agca, agc1, im:7146049
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 6 figures from 6 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7146049]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  basibranchial, ceratobranchial bone, ceratohyal bone, ceratohyal cartilage (all 16) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH acana HUMAN ORTHOLOG 
Disease Ontology Term OMIM Term OMIM Phenotype ID
osteochondritis dissecans Osteochondritis dissecans, short stature, and early-onset osteoarthritis 165800
Spondyloepimetaphyseal dysplasia, aggrecan type 612813
Spondyloepiphyseal dysplasia, Kimberley type 608361
GENE ONTOLOGY 
Ontology GO Term
Biological Process cell adhesion (more)
Cellular Component proteinaceous extracellular matrix (more)
Molecular Function calcium ion binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000436 (1)
  • InterPro:IPR000538 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001304 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013106 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR016186 (1)
  • InterPro:IPR016187 (1)
  • InterPro:IPR018378 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS00615 (1)
  • PROSITE:PS01241 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50041 (1)
  • PROSITE:PS50835 (1)
  • PROSITE:PS50923 (1)
  • PROSITE:PS50963 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF00059 (1)
  • Pfam:PF00084 (1)
  • Pfam:PF00193 (1)
  • Pfam:PF07686 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acana-001 (1) 2132
    acana-002 (1) 1033
    acana-003 (1) 507
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acana No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    acanaContained in: [BAC] DKEY-56P7 (1) (order this)
    acanaEncodes: [EST] IMAGE:7146049 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005166485 (1) 7552bp
    Genomic GenBank:AL929208 (1) 189608bp
    Select Tool
    Polypeptide UniProtKB:E7F537 (1) 1833aa
    Sequence Clusters UniGene:89851 (1)
    Sequence Information (all 21)
    OTHER acana GENE PAGES 
  • Gene:497505 (1)
  • VEGA:OTTDARG00000011677 (1)
  • Ensembl(GRCz10):ENSDARG00000035891 (1)
  • ORTHOLOGY for acana (Chr: 7) 
    Species Symbol Chromosome Accession # Evidence
    Human ACAN 15
  • Gene:176
  • OMIM:155760
  • HGNC:319
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Acan 7
  • MGI:99602
  • Gene:11595
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (21)