ZFIN ID: ZDB-GENE-050208-221
Gene Name: aggrecan a
Gene Symbol: acana
Previous Names: agc1, agca, im:7146049
Location: Chr: 7   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 4 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7146049]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  basibranchial, ceratobranchial bone, ceratohyal bone, ceratohyal cartilage (all 15) expand
MUTANTS AND TARGETED KNOCKDOWNS No data available
PHENOTYPE
Phenotype of Human Orthologue OMIM Phenotype ID
Osteochondritis dissecans, short stature, and early-onset osteoarthritis 165800
Spondyloepimetaphyseal dysplasia, aggrecan type 612813
Spondyloepiphyseal dysplasia, Kimberley type 608361
GENE ONTOLOGY
Ontology GO Term
Biological Process cell adhesion (more)
Cellular Component proteinaceous extracellular matrix (more)
Molecular Function hyaluronic acid binding (more)
GO Terms (all 6)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000436 (1)
  • InterPro:IPR000538 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001304 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013106 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR016186 (1)
  • InterPro:IPR016187 (1)
  • InterPro:IPR018378 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS00615 (1)
  • PROSITE:PS01241 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50041 (1)
  • PROSITE:PS50835 (1)
  • PROSITE:PS50923 (1)
  • PROSITE:PS50963 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF00059 (1)
  • Pfam:PF00084 (1)
  • Pfam:PF00193 (1)
  • Pfam:PF07686 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acana-001 (1) 2132
    acana-002 (1) 1033
    acana-003 (1) 507
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM acana No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    acana Contained in: [BAC] DKEY-56P7 (1)
    acana Encodes: [EST] IMAGE:7146049 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005166485 (1) 7552 bp
    Genomic GenBank:AL929208 (1) 189608 bp
    Select Tool
    Polypeptide UniProtKB:E7F537 (1) 1831 aa
    Sequence Clusters UniGene:89851 (1)
    Sequence Information (all 20)
    OTHER acana GENE PAGES
  • Gene:497505 (1)
  • VEGA:OTTDARG00000011677 (1)
  • Ensembl(Zv9):ENSDARG00000035891 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish acana 7  
    Human ACAN 15 (15q26.1)
  • OMIM:155760
  • Gene:176
  • Mouse Acan 7 ( 44.88 cM)
  • MGI:99602
  • Gene:11595
  • Orthology Details
    CITATIONS (16)