ZFIN ID: ZDB-GENE-050208-221
Gene Name: aggrecan a
Gene Symbol: acana

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Previous Names: agca, agc1, im:7146049

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Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 7 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7146049]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  basibranchial, ceratobranchial bone, ceratohyal bone, ceratohyal cartilage (all 21) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa7281 Point Mutation Unknown Premature Stop ENU
sa31591 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40999 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH acana HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    osteochondritis dissecans Osteochondritis dissecans, short stature, and early-onset osteoarthritis 165800
    Spondyloepiphyseal dysplasia, Kimberley type 608361
    Spondyloepimetaphyseal dysplasia, aggrecan type 612813
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process cell adhesion (more)
    Cellular Component proteinaceous extracellular matrix (more)
    Molecular Function calcium ion binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000436 (1)
  • InterPro:IPR000538 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001304 (1)
  • InterPro:IPR001881 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013106 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR016186 (1)
  • InterPro:IPR016187 (1)
  • InterPro:IPR018378 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS00615 (1)
  • PROSITE:PS01241 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50041 (1)
  • PROSITE:PS50835 (1)
  • PROSITE:PS50923 (1)
  • PROSITE:PS50963 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF00059 (1)
  • Pfam:PF00084 (1)
  • Pfam:PF00193 (1)
  • Pfam:PF07686 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acana-001 (1) 6000
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM acana No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    acanaContained in: [BAC] DKEY-56P7 (1) (order this)
    acanaEncodes: [EST] IMAGE:7146049 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005166485 (1) 6384bp
    Genomic GenBank:AL929208 (1) 189608bp
    Select Tool
    Polypeptide UniProtKB:E7F537 (1) 1833aa
    Sequence Clusters UniGene:89851 (1)
    Sequence Information (all 21)
    OTHER acana GENE PAGES
  • Gene:497505 (1)
  • VEGA:OTTDARG00000011677 (1)
  • Ensembl(GRCz10):ENSDARG00000035891 (1)
  • ORTHOLOGY for acana (Chr: 7)
    Species Symbol Chromosome Accession # Evidence
    Human ACAN 15
  • Gene:176
  • OMIM:155760
  • HGNC:319
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Acan 7
  • MGI:99602
  • Gene:11595
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (23)