ZFIN ID: ZDB-GENE-050208-221
Gene Name: aggrecan a
Gene Symbol: acana
Previous Names: agca, agc1, im:7146049
Location: Chr: 7 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 5 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7146049]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
  basibranchial, ceratobranchial bone, ceratohyal bone, ceratohyal cartilage (all 15) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH acana HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
osteochondritis dissecans Osteochondritis dissecans, short stature, and early-onset osteoarthritis 165800
Spondyloepimetaphyseal dysplasia, aggrecan type 612813
Spondyloepiphyseal dysplasia, Kimberley type 608361
GENE ONTOLOGY
Ontology GO Term
Biological Process cell adhesion (more)
Cellular Component integral component of membrane (more)
Molecular Function hyaluronic acid binding (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000436 (1)
  • InterPro:IPR000538 (1)
  • InterPro:IPR000742 (1)
  • InterPro:IPR001304 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR013032 (1)
  • InterPro:IPR013106 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR016186 (1)
  • InterPro:IPR016187 (1)
  • InterPro:IPR018378 (1)
  • PROSITE:PS00022 (1)
  • PROSITE:PS00615 (1)
  • PROSITE:PS01241 (1)
  • PROSITE:PS50026 (1)
  • PROSITE:PS50041 (1)
  • PROSITE:PS50835 (1)
  • PROSITE:PS50923 (1)
  • PROSITE:PS50963 (1)
  • Pfam:PF00008 (1)
  • Pfam:PF00059 (1)
  • Pfam:PF00084 (1)
  • Pfam:PF00193 (1)
  • Pfam:PF07686 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA acana-001 (1) 2132
    acana-002 (1) 1033
    acana-003 (1) 507
    GENE PRODUCT DESCRIPTION
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM acana No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    acanaContained in: [BAC] DKEY-56P7 (1) (order this)
    acanaEncodes: [EST] IMAGE:7146049 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005166485 (1) 7552bp
    Genomic GenBank:AL929208 (1) 189608bp
    Select Tool
    Polypeptide UniProtKB:E7F537 (1) 1831aa
    Sequence Clusters UniGene:89851 (1)
    Sequence Information (all 20)
    OTHER acana GENE PAGES
  • Gene:497505 (1)
  • VEGA:OTTDARG00000011677 (1)
  • Ensembl(GRCz10):ENSDARG00000035891 (1)
  • ORTHOLOGY for acana (Chr: 7)
    Species Symbol Chromosome Accession # Evidence
    Human ACAN 15
  • Gene:176
  • OMIM:155760
  • HGNC:319
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Acan 7
  • MGI:99602
  • Gene:11595
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (21)