Gene

eif5b

ID

ZDB-GENE-050208-20

Name

eukaryotic translation initiation factor 5B

Symbol

eif5b Nomenclature History

Previous Names

im:6912504 (1)
si:ch211-254d18.3 (1)

Type

protein_coding_gene

Location

Chr: 1 Mapping Details/Browsers

Description

Predicted to enable translation initiation factor activity. Predicted to be involved in translational initiation. Predicted to act upstream of or within translation. Predicted to be active in cytoplasm. Orthologous to human EIF5B (eukaryotic translation initiation factor 5B).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

1 figure from Thisse et al., 2004

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:6912504 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With eif5b Human Ortholog

No data available

Associated With eif5b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000795	Translational (tr)-type GTP-binding domain
Domain	IPR005225	Small GTP-binding domain
Domain	IPR023115	Translation initiation factor IF- 2, domain 3
Domain	IPR029459	Elongation factor Tu-type domain
Family	IPR015760	Translation initiation factor IF- 2
Homologous_superfamily	IPR009000	Translation protein, beta-barrel domain superfamily
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036925	Translation initiation factor IF-2, domain 3 superfamily

Domain Details Per Protein

Protein	Length	Elongation factor Tu-type domain	P-loop containing nucleoside triphosphate hydrolase	Small GTP-binding domain	Translational (tr)-type GTP-binding domain	Translation initiation factor IF- 2	Translation initiation factor IF- 2, domain 3	Translation initiation factor IF-2, domain 3 superfamily	Translation protein, beta-barrel domain superfamily
UniProtKB:A0A8M1QHW9 InterPro	1231
UniProtKB:A0A8M3AKJ3 InterPro	1229

Transcripts

Genome Browsers

NCBI

Ensembl

ZFIN

Type	Name	Annotation Method	Has Havana Data	Length (nt)	Analysis
mRNA	eif5b-201 (1) Ensembl	Ensembl		8,064 nt	Select Tool ZFIN BLAST
mRNA	eif5b-202 (1) Ensembl	Ensembl		938 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations