ZFIN Gene: eif5b

ZFIN ID: ZDB-GENE-050208-20

ZFIN ID: ZDB-GENE-050208-20

Gene Name:

eukaryotic translation initiation factor 5B

Gene Symbol:

eif5b Nomenclature History

Previous Names:

im:6912504 (1), si:ch211-254d18.3 (1)

Gene Type:

protein_coding_gene

Location:

Description:

Predicted to have translation initiation factor activity. Orthologous to human EIF5B (eukaryotic translation initiation factor 5B).

Genome Resources:

Alliance (1), Gene:561194 (1), Ensembl(GRCz11):ENSDARG00000016548 (2)

GENE EXPRESSION
Directly Submitted Expression Data:	1 figure (1 image) from Thisse et al., 2004 [IMAGE:6912504]
Wild-type Stages, Structures:	Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
	unspecified
High Throughput Expression:	GEO (1) , Expression Atlas (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa32742	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa32743	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this)
sa38289	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
zko894a	Insertion	Unknown	Unknown	CRISPR	China Zebrafish Resource Center (CZRC) (order this)
zko894b	Small Deletion	Unknown	Unknown	CRISPR	China Zebrafish Resource Center (CZRC) (order this)

Sequence Targeting Reagents

Targeting Reagent	Created Alleles	Publications
CRISPR1-eif5b	zko894a zko894b	1

PHENOTYPE No data available

DISEASE ASSOCIATED WITH eif5b HUMAN ORTHOLOG No data available

DISEASE ASSOCIATED WITH eif5b VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Molecular Function	GTPase activity (more)

GO Terms (all 3)

PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available

TRANSCRIPTS
Type	Name	Length (nt)	Analysis
mRNA	eif5b-202 (1)	938	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Browsers: NCBI, Ensembl, ZFIN

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM eif5b No data available

MARKER RELATIONSHIPS

eif5b Contained in:	[BAC] CH211-254D18 (1)
eif5b Encodes:	[EST] IMAGE:6912504 (1)

SEQUENCE INFORMATION

Type	Accession #	Length (nt/aa)	Analysis
RNA	RefSeq:XM_001923538 (1)		Select Tool ZFIN BLAST NCBI BLAST MegaBLAST Ensembl UCSC BLAT
Genomic	GenBank:BX901938 (1)	104059 nt	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:F1QB47 (1)	1265 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast

ORTHOLOGY for eif5b ( Chr: 1 )

CITATIONS (20)