ZFIN ID: ZDB-GENE-050114-5
Gene Name: EDAR-associated death domain
Gene Symbol: edaradd
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 17 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: Fig. S5 from Aigler et al., 2014
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  mouth
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa23062 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-edaradd (1), MO2-edaradd (1)
    PHENOTYPE
    Data: Fig. 5 from Sadier et al., 2015
    Observed in: ceratobranchial 5 primary tooth, chondrocranium cartilage, pharyngeal arch 3-7 skeleton, splanchnocranium (all 6) expand
    DISEASE ASSOCIATED WITH edaradd HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Ectodermal dysplasia 11A, hypohidrotic/hair/tooth type, autosomal dominant 614940
    Ectodermal dysplasia 11B, hypohidrotic/hair/tooth type, autosomal recessive 614941
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic viscerocranium morphogenesis (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000488 (1)
  • InterPro:IPR011029 (1)
  • Pfam:PF00531 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA edaradd-001 (1) 1887
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM edaradd No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    edaraddContained in: [BAC] CH211-125O16 (1) (order this)
    edaraddEncodes: [STS] zfish44908-2681g11.p1k
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_690046 (1) 1969bp
    Genomic GenBank:BX511245 (1) 96687bp
    Select Tool
    Polypeptide UniProtKB:E7F388 (1) 219aa
    Sequence Information (all 4)
    OTHER edaradd GENE PAGES
  • Gene:566761 (1)
  • VEGA:OTTDARG00000035121 (1)
  • Ensembl(GRCz10):ENSDARG00000062289 (1)
  • ORTHOLOGY for edaradd (Chr: 17)
    CITATIONS (10)