ZFIN Gene: lmx1ba

ZFIN ID: ZDB-GENE-050114-3

ZFIN ID: ZDB-GENE-050114-3

Gene Name:

LIM homeobox transcription factor 1, beta a

Gene Symbol:

lmx1ba

Sequence Ontology ID :

SO:0001217

Previous Name:

lmx1b.2

Location:

Chr: 5 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in animal organ ...

GENE EXPRESSION
All Expression Data:	15 figures from 9 publications
Wild-type Stages, Structures:	Gastrula:90%-epiboly (9.0h-10.0h) to Adult (90d-730d, breeding adult)
	amacrine cell axis diencephalon ventral region diencephalon eye fin bud floor plate heart hindbrain roof plate hindbrain hindbrain neural keel inferior raphe nucleus interneuron margin midbrain midbrain hindbrain boundary midbrain hindbrain boundary neural rod midbrain neural rod neural plate optic furrow optic stalk periocular mesenchyme pronephros roof plate roof plate midbrain region serotonergic neuron spinal cord cell spinal cord superior raphe nucleus tectal ventricle unspecified

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
la015718Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la015720Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
la025125Tg	Transgenic Insertion	Unknown	Unknown	DNA	Zebrafish International Resource Center (ZIRC) (order this)
mw80	Small Deletion	Unknown	Frameshift, Premature Stop

Targeting reagents:

PHENOTYPE

Data:	3 figures from 3 publications
Observed in:	fourth ventricle fourth ventricle development glutamatergic neuron heart pronephric glomerulus

DISEASE ASSOCIATED WITH lmx1ba HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
nail-patella syndrome	Nail-patella syndrome	161200

DISEASE ASSOCIATED WITH lmx1ba VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	closure of optic fissure (more)
Cellular Component	nucleus (more)
Molecular Function	DNA binding (more)

GO Terms (all 17)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR001356 (1) InterPro:IPR001781 (1) InterPro:IPR009057 (1) InterPro:IPR017970 (1)	PROSITE:PS00027 (1) PROSITE:PS00478 (1) PROSITE:PS50023 (1) PROSITE:PS50071 (1)	Pfam:PF00046 (1) Pfam:PF00412 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	lmx1ba-202 (1)	185	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION

INTERACTIONS AND PATHWAYS

ANTIBODIES No data available

PLASMIDS No data available

CONSTRUCTS WITH SEQUENCES FROM lmx1ba No data available

MARKER RELATIONSHIPS

lmx1ba Contained in:	[BAC] RP71-14I8 (1) (order this)
lmx1ba Encodes:	[cDNA] MGC:194681 (1) (order this), MGC:194704 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:NM_001025168 (1)	2076 bp	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
Genomic	GenBank:BX511196 (1)	143654 bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:Q4L1M5 (1)	375 aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:94065 (1)

Sequence Information (all 33)

OTHER lmx1ba GENE PAGES

Alliance (1)

Gene:554361 (1)

VEGA:OTTDARG00000015761 (1)

Ensembl(GRCz11):ENSDARG00000104815 (1)

ORTHOLOGY for lmx1ba ( Chr: 5 )

CITATIONS (34)

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