Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-050114-2
Gene Name: LIM homeobox transcription factor 1, beta b
Gene Symbol: lmx1bb
Previous Names: lmx1b (1), lmx1b.1, alo (1)
Location: Chr: 8   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 20 figures from 11 publications
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
  amacrine cell, axis, caudal tuberculum, diencephalon (all 34) expand
MUTANTS AND TARGETED KNOCKDOWNS
Mutant lines: 2 genotypes
Alleles: jj410, la016356Tg, sa14923
Knockdown reagents: MO1-lmx1bb (1), MO2-lmx1bb (1)
PHENOTYPE
Data: 5 figures from 2 publications
Observed in: anterior crista, ball, brain, eye (all 11) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Nail-patella syndrome 161200
GENE ONTOLOGY
Ontology GO Term
Biological Process closure of optic fissure (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 16)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR001781 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00478 (1)
  • PROSITE:PS50023 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF00412 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lmx1bb-001 (1) 1952
    ncRNA lmx1bb-002 (1) 697
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM lmx1bb
    Tg(-5.0lmx1bb:GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lmx1bb Contained in: [BAC] CH211-81G2 (1) (order this), CH211-101A21 (1) (order this), DKEY-17A16 (1)
    lmx1bb Encodes: [cDNA] MGC:194366 (1) (order this), MGC:194387 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001025167 (1) 1952 bp
    Genomic GenBank:CR376762 (1) 183602 bp
    Select Tool
    Polypeptide UniProtKB:Q4L1M6 (1) 375 aa
    Sequence Clusters UniGene:108678 (1)
    Sequence Information (all 25)
    OTHER lmx1bb GENE PAGES
  • Gene:554360 (1)
  • VEGA:OTTDARG00000020391 (1)
  • Ensembl(Zv9):ENSDARG00000068365 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish lmx1bb 8  
    Human LMX1B 9 (9q33.3)
  • OMIM:602575
  • Gene:4010
  • Mouse Lmx1b 2 ( 22.48 cM)
  • MGI:1100513
  • Gene:16917
  • Orthology Details
    CITATIONS (36)