ZFIN ID: ZDB-GENE-050114-2
Gene Name: LIM homeobox transcription factor 1, beta b
Gene Symbol: lmx1bb

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: lmx1b.1, lmx1b (1), alo (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 8 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 20 figures from 11 publications
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Adult (90d-730d, breeding adult)
  amacrine cell, axis, caudal tuberculum, diencephalon (all 42) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
jj410 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la016356Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14923 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34444 Point Mutation Unknown Splice Site ENU
    sa34445 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41254 Point Mutation Unknown Premature Stop ENU
    Targeting reagents: MO1-lmx1bb (1), MO2-lmx1bb (1)
    PHENOTYPE
    Data: 7 figures from 3 publications
    Observed in: anterior crista, ball, brain, eye (all 17) expand
    DISEASE ASSOCIATED WITH lmx1bb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    nail-patella syndrome Nail-patella syndrome 161200
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process closure of optic fissure (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR001781 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS00478 (1)
  • PROSITE:PS50023 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF00412 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lmx1bb-001 (1) 1952
    ncRNA lmx1bb-002 (1) 697
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lmx1bb
    Tg(-5.0lmx1bb:GFP)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    lmx1bbContained in: [BAC] CH211-81G2 (1) (order this), CH211-101A21 (1) (order this), DKEY-17A16 (1) (order this)
    lmx1bbEncodes: [cDNA] MGC:194366 (1) (order this), MGC:194387 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001025167 (1) 1952bp
    Genomic GenBank:CR376762 (1) 183602bp
    Select Tool
    Polypeptide UniProtKB:Q4L1M6 (1) 375aa
    Sequence Clusters UniGene:108678 (1)
    Sequence Information (all 26)
    OTHER lmx1bb GENE PAGES
  • Gene:554360 (1)
  • VEGA:OTTDARG00000020391 (1)
  • Ensembl(GRCz10):ENSDARG00000068365 (1)
  • ORTHOLOGY for lmx1bb (Chr: 8)
    Species Symbol Chromosome Accession # Evidence
    Human LMX1B 9
  • Gene:4010
  • OMIM:602575
  • HGNC:6654
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Lmx1b 2
  • MGI:1100513
  • Gene:16917
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (38)