Gene

ezh1

ID
ZDB-GENE-050114-1
Name
enhancer of zeste 1 polycomb repressive complex 2 subunit
Symbol
ezh1 Nomenclature History
Previous Names
  • si:ch211-250i3.1
  • zgc:136829
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable histone-lysine N-methyltransferase activity. Predicted to act upstream of or within histone H3-K27 methylation. Predicted to be located in nucleus. Is expressed in several structures, including blastomere; eye; gonad; gut; and pectoral fin bud. Orthologous to human EZH1 (enhancer of zeste 1 polycomb repressive complex 2 subunit).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
8 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Völkel et al., 2019
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ezh1 Human Ortholog
No data available
Associated With ezh1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001005 SANT/Myb domain
Domain IPR001214 SET domain
Domain IPR026489 CXC domain
Domain IPR033467 Tesmin/TSO1-like CXC domain
Domain IPR041343 Polycomb repressive complex 2 subunit EZH1/EZH2, tri-helical domain
Domain IPR041355 Pre-SET CXC domain
Family IPR021654 Histone-lysine N-methyltransferase EZH1/EZH2
Family IPR032926 Histone-lysine N-methyltransferase EZH1
Domain Details Per Protein
Protein Length CXC domain Histone-lysine N-methyltransferase EZH1 Histone-lysine N-methyltransferase EZH1/EZH2 Polycomb repressive complex 2 subunit EZH1/EZH2, tri-helical domain Pre-SET CXC domain SANT/Myb domain SET domain Tesmin/TSO1-like CXC domain
UniProtKB:E7FFB7 756
UniProtKB:Q29RB7 147
UniProtKB:A5XBQ4 153
UniProtKB:F8W619 749
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations