Gene
eda
- ID
- ZDB-GENE-050107-6
- Name
- ectodysplasin A
- Symbol
- eda Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Predicted to have tumor necrosis factor receptor binding activity. Involved in bone development and odontogenesis. Predicted to localize to membrane. Human ortholog(s) of this gene implicated in ectodermal dysplasia 1 and tooth agenesis. Is expressed in dental mesenchyme; integument; pharyngeal arch; and pharynx. Orthologous to human EDA (ectodysplasin A).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 7 figures from 6 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ectodermal dysplasia 1 | Alliance | Ectodermal dysplasia 1, hypohidrotic, X-linked | 305100 |
| tooth agenesis | Alliance | Tooth agenesis, selective, X-linked 1 | 313500 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Tumour necrosis factor domain | Tumour necrosis factor-like domain superfamily |
|---|---|---|---|
|
UniProtKB:B0YIF1
|
359 | ||
|
UniProtKB:A0A8M9PKL3
|
354 | ||
|
UniProtKB:A0A8M9QEC5
|
357 | ||
|
UniProtKB:A0A8M9Q921
|
356 |
Interactions and Pathways
No data available
Plasmids
No data available