Gene

eda

ID
ZDB-GENE-050107-6
Name
ectodysplasin A
Symbol
eda Nomenclature History
Previous Names
  • nackt (1)
  • nkt (1)
  • si:ch73-223d24.5 (1)
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Predicted to have death receptor agonist activity and death receptor binding activity. Involved in bone development and odontogenesis. Predicted to localize to plasma membrane. Is expressed in dental mesenchyme; integument; pharyngeal arch; and pharynx. Human ortholog(s) of this gene implicated in ectodermal dysplasia 1 and tooth agenesis. Orthologous to human EDA (ectodysplasin A).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 6 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
6 figures from 4 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With eda Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Ectodermal dysplasia 1, hypohidrotic, X-linked 305100
Tooth agenesis, selective, X-linked 1 313500
Associated With eda Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006052 Tumour necrosis factor domain
Homologous_superfamily IPR008983 Tumour necrosis factor-like domain superfamily
Domain Details Per Protein
Protein Length Tumour necrosis factor domain Tumour necrosis factor-like domain superfamily
UniProtKB:B0YIF1 359
UniProtKB:A0A8M9PKL3 354
UniProtKB:A0A8M9QEC5 357
UniProtKB:A0A8M9Q921 356
Transcripts
Genome Browsers
Type Name Annotation Method Length (nt) Analysis
mRNA eda-201 (1) Havana 1216 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations