ZFIN ID: ZDB-GENE-050107-6
Gene Name: ectodysplasin A
Gene Symbol: eda
Sequence Ontology ID : SO:0000704

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Previous Names: nackt (1), nkt (1), si:ch73-223d24.5 (1)

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Juvenile:Days 30-44 (30d-45d, 10 mm, adult fins/pigment)
  dental mesenchyme, epidermis, pharyngeal arch, pharynx (all 5) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
dt1261 Point Mutation Unknown Unknown ENU
la015662Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31463 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31464 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • PHENOTYPE
    Data: 3 figures from 2 publications
    Observed in: anal fin lepidotrichium, caudal fin lepidotrichium, ceratobranchial 5 tooth, cranium (all 10) expand
    DISEASE ASSOCIATED WITH eda HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    hypohidrotic ectodermal dysplasia Ectodermal dysplasia 1, hypohidrotic, X-linked 305100
    tooth agenesis Tooth agenesis, selective, X-linked 1 313500
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process bone development (more)
    Cellular Component membrane (more)
    Molecular Function tumor necrosis factor receptor binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006052 (1)
  • InterPro:IPR008983 (1)
  • InterPro:IPR016133 (1)
  • PROSITE:PS50049 (1)
  • Pfam:PF00229 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA eda-001 (1) 1216
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM eda
    Tg(Xla.Eef1a1:eda)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    edaContained in: [BAC] CH73-78E11 (1) (order this), CH73-223D24 (1) (order this), DKEY-48F17 (1) (order this)
    edaContains: [STS] z35723-a1228g06.q1c (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001115065 (1) 1216bp
    Genomic GenBank:AL954373 (1) 220092bp Blast at MegaBLAST
    Polypeptide UniProtKB:B0YIF1 (1) 359aa
    Sequence Clusters UniGene:97008 (1)
    Sequence Information (all 11)
    OTHER eda GENE PAGES
  • Gene:798740 (1)
  • VEGA:OTTDARG00000029159 (1)
  • Ensembl(GRCz10):ENSDARG00000074591 (1)
  • ORTHOLOGY for eda (Chr: 5)
    CITATIONS (21)