Gene
gnsa
- ID
- ZDB-GENE-050107-5
- Name
- glucosamine (N-acetyl)-6-sulfatase a
- Symbol
- gnsa Nomenclature History
- Previous Names
-
- gnsl
- zgc:114066
- Type
- protein_coding_gene
- Location
- Chr: 4 Mapping Details/Browsers
- Description
- Predicted to have N-acetylglucosamine-6-sulfatase activity and glycosaminoglycan binding activity. Predicted to be involved in glycosaminoglycan metabolic process. Predicted to localize to lysosome. Human ortholog(s) of this gene implicated in mucopolysaccharidosis III and mucopolysaccharidosis type IIID. Orthologous to human GNS (glucosamine (N-acetyl)-6-sulfatase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| mucopolysaccharidosis III | Alliance | Mucopolysaccharidosis type IIID | 252940 |
| mucopolysaccharidosis type IIID | Alliance | Mucopolysaccharidosis type IIID | 252940 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Alkaline-phosphatase-like, core domain superfamily | N-acetylglucosamine-6-sulfatase | Sulfatase, conserved site | Sulfatase, N-terminal |
|---|---|---|---|---|---|
|
UniProtKB:Q4V902
|
538 |
Interactions and Pathways
No data available
Plasmids
No data available