ZFIN ID: ZDB-GENE-050107-4
Gene Name: patatin-like phospholipase domain containing 6
Gene Symbol: pnpla6
Sequence Ontology ID : SO:0000704

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Previous Names: nte (1), wu:fy20f06

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have lysophospholipase activity; involved in anterior/posterior axis specification, axonogenesis, and negative regulation of BMP signaling pathway; predicted to localize to the  ...
GENE EXPRESSION No data available
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la021234Tg Transgenic Insertion Unknown Unknown DNA
la028165Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14069 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17978 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32741 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko892a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • zko892b Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 4 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH pnpla6 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    hereditary spastic paraplegia 39 Spastic paraplegia 39, autosomal recessive 612020
    Laurence-Moon syndrome ?Laurence-Moon syndrome 245800
    Oliver-McFarlane syndrome 275400
    Boucher-Neuhauser syndrome 215470
    DISEASE ASSOCIATED WITH pnpla6 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process anterior/posterior axis specification (more)
    Cellular Component endoplasmic reticulum (more)
    Molecular Function carboxylic ester hydrolase activity (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000595 (1)
  • InterPro:IPR001423 (1)
  • InterPro:IPR002641 (1)
  • InterPro:IPR014710 (1)
  • InterPro:IPR016035 (1)
  • InterPro:IPR018490 (1)
  • PROSITE:PS01237 (1)
  • PROSITE:PS50042 (1)
  • PROSITE:PS51635 (1)
  • Pfam:PF00027 (1)
  • Pfam:PF01734 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pnpla6-201 (1) 771
    pnpla6-202 (1) 7644
    pnpla6-203 (1) 638
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pnpla6 No data available
    MARKER RELATIONSHIPS
    pnpla6Contained in: [BAC] CH211-254D18 (1) (order this)
    pnpla6Contains: [STS] z35724-a2618a09.q1c (1)
    pnpla6Encodes: [EST] fy20f06 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_005160052 (1) 7304bp
    Genomic GenBank:BX901938 (1) 104059bp
    Select Tool
    Polypeptide UniProtKB:F1R844 (1) 1342aa
    Sequence Clusters UniGene:108408 (1)
    Sequence Information (all 16)
    OTHER pnpla6 GENE PAGES
  • Alliance (1)
  • Gene:560986 (1)
  • VEGA:OTTDARG00000030076 (1)
  • Ensembl(GRCz11):ENSDARG00000010773 (2)
  • ORTHOLOGY for pnpla6 (Chr: 1)
    CITATIONS (25)