ZFIN ID: ZDB-GENE-050107-1
Gene Name: erb-b2 receptor tyrosine kinase 3b
Gene Symbol: erbb3b
Sequence Ontology ID : SO:0000704

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Attributions

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Previous Names: hps, hypersensitive (1), pcs, picasso

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have transmembrane receptor protein tyrosine kinase activity; involved in several processes, including fin regeneration, lateral line system development, and nervous system development;  ...
GENE EXPRESSION
All Expression Data: 5 figures from 5 publications
Wild-type Stages, Structures: Pharyngula:Prim-15 (30.0h-36.0h) to Larval:Days 14-20 (14d-21d, 6.2mm, 10 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
erbb3b_unspecified Unspecified Unknown Unknown
hg115 Small Deletion Unknown Unknown CRISPR
sa5978 Point Mutation Unknown Splice Site ENU
sa8650 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14974 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa18520 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29934 Point Mutation Unknown Premature Stop ENU
    sa37713 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37714 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • st14 Point Mutation Unknown Missense ENU
    st48 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • t5419 Unknown Unknown Unknown
    t20458 Point Mutation Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • t21411 Unknown Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • t23877 Point Mutation Unknown Unknown
  • European Zebrafish Resource Center (EZRC) (order this)
  • tc288d Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • utr2e1 Point Mutation Unknown Unknown ENU
    wpr2e2 Point Mutation Unknown Unknown ENU
    zf165 Point Mutation Unknown Premature Stop
    Targeting reagents:
    PHENOTYPE
    Data: 25 figures from 11 publications
    Observed in:
    DISEASE ASSOCIATED WITH erbb3b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    lethal congenital contracture syndrome 2 ?Lethal congenital contractural syndrome 2 607598
    {?Erythroleukemia, familial, susceptibility to} 133180
    {?Erythroleukemia, familial, susceptibility to} 133180
    DISEASE ASSOCIATED WITH erbb3b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonal fasciculation (more)
    Cellular Component integral component of membrane (more)
    Molecular Function protein kinase activity (more)
    GO Terms (all 24)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000494 (1)
  • InterPro:IPR000719 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR006211 (1)
  • InterPro:IPR006212 (1)
  • InterPro:IPR009030 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR016245 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR032778 (1)
  • InterPro:IPR036941 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS50011 (1)
  • Pfam:PF00757 (1)
  • Pfam:PF01030 (1)
  • Pfam:PF07714 (1)
  • Pfam:PF14843 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA erbb3b-202 (1) 4636
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM erbb3b No data available
    MARKER RELATIONSHIPS
    erbb3bContained in: [BAC] DKEY-151G10 (order this)
    erbb3bContains: [STS] zfish37251-627a06.p1c (1)
    erbb3bEncodes: [EST] fi48d12 (1)
    [cDNA] MGC:193982 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001014826 (1) 4644bp
    Genomic GenBank:CR382340 (1) 158509bp
    Select Tool
    Polypeptide UniProtKB:B3DH46 (1) 1429aa
    Sequence Clusters UniGene:154671 (1)
    Sequence Information (all 22)
    OTHER erbb3b GENE PAGES
  • Alliance (1)
  • Gene:544664 (1)
  • VEGA:OTTDARG00000021301 (1)
  • ORTHOLOGY for erbb3b (Chr: 23)
    CITATIONS (57)