Gene
trpa1a
- ID
- ZDB-GENE-050105-6
- Name
- transient receptor potential cation channel, subfamily A, member 1a
- Symbol
- trpa1a Nomenclature History
- Previous Names
-
- trpa1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 2 Mapping Details/Browsers
- Description
- Exhibits calcium-release channel activity and mechanosensitive ion channel activity. Involved in detection of chemical stimulus; detection of mechanical stimulus involved in sensory perception; and ion transmembrane transport. Predicted to localize to integral component of membrane. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 1. Is expressed in integument; keratinocyte; and vagal ganglion 4. Orthologous to human TRPA1 (transient receptor potential cation channel subfamily A member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 4 figures from 3 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| familial episodic pain syndrome 1 | Alliance | ?Episodic pain syndrome, familial, 1 | 615040 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Ankyrin repeat | Ankyrin repeat-containing domain superfamily | Ion transport domain | Transient receptor potential cation channel |
|---|---|---|---|---|---|
|
UniProtKB:Q5UM15
|
1115 | ||||
|
UniProtKB:A0A8M6Z942
|
1115 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
trpa1a-201
(1)
|
Ensembl | 4,245 nt |
Interactions and Pathways
No data available
Plasmids
No data available