ZFIN ID: ZDB-GENE-050105-3
Gene Name: solute carrier family 6 member 9
Gene Symbol: slc6a9    Nomenclature History

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Previous Names: glyt1 (2), sho, shocked

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Exhibits glycine transmembrane transporter activity. Involved in several processes, including glycine transport; inhibitory postsynaptic potential; and regulation of glycinergic synaptic transmission. Predicted to localize to the plasma membrane. Is expressed in fourth ventricle; hindbrain; neural rod; optic tectum; and spinal cord. Orthologous to human SLC6A9 (solute carrier family 6 member 9).
Genome Resources: Alliance (1),  Gene:494490 (1),  Ensembl(GRCz11):ENSDARG00000018534 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023611Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19804 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19805 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39868 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • ta51e Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • ta229g Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • te301 Unknown Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-slc6a9 N/A 1
    DISEASE ASSOCIATED WITH slc6a9 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Glycine encephalopathy with normal serum glycine 617301
    DISEASE ASSOCIATED WITH slc6a9 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process glycine transport (more)
    Cellular Component integral component of membrane (more)
    Molecular Function glycine transmembrane transporter activity (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Family IPR000175 Sodium:neurotransmitter symporter
    Family IPR003028 Sodium:neurotransmitter symporter, glycine, type 1
    Homologous_superfamily IPR037272 Sodium:neurotransmitter symporter superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA slc6a9-201 (1)    Ensembl 9709
    slc6a9-204 (1)    Ensembl 254
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM slc6a9 No data available
    MARKER RELATIONSHIPS
    slc6a9 Contained in: [BAC] CH211-261P7 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030073 (1) 1935 bp
    Genomic GenBank:BX537271 (1) 169504 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8RP73 (1) 653 aa
    Sequence Information (all 22)
    ORTHOLOGY for slc6a9 ( Chr: 2 )
    CITATIONS (37)