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ZIRC
ZFIN ID: ZDB-GENE-050102-2
Gene Name: A-Raf proto-oncogene, serine/threonine kinase
Gene Symbol: araf
Sequence Ontology ID : SO:0000704

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Previous Names: sb:eu994, wu:fk45h07, zgc:92074

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(Including Attributions)
Location: Chr: 5 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits SMAD binding activity. Involved in negative regulation of nodal signaling pathway and pathway-restricted SMAD protein phosphorylation. Predicted to localize to the cytosol and mitochondrion.  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2005 [eu994]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
Curated Microarray Expression: GEO (1)
DISEASE ASSOCIATED WITH araf HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH araf VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process negative regulation of nodal signaling pathway (more)
Cellular Component cytosol (more)
Molecular Function SMAD binding (more)
GO Terms (all 22)
TRANSCRIPTS
Type Name Length (bp) Analysis
mRNA araf-203 (1) 1210
araf-204 (1) 6809
araf-205 (1) 6779
GENE PRODUCT DESCRIPTION No description available
INTERACTIONS AND PATHWAYS
ANTIBODIESNo data available
PLASMIDSNo data available
CONSTRUCTS WITH SEQUENCES FROM araf No data available
MARKER RELATIONSHIPS
arafContained in: [BAC] CH211-102C2 (1) (order this)
arafEncodes: [EST] eu994 (1), fk45h07
[cDNA] MGC:92074 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_205743 (1) 3488bp
Genomic GenBank:CU041374 (1) 141040bp
Select Tool
Polypeptide UniProtKB:Q5FBD1 (1) 608aa
Sequence Clusters UniGene:77625 (1)
Sequence Information (all 48)
ORTHOLOGY for araf (Chr: 5)
CITATIONS (19)