Gene

dhcr24

ID
ZDB-GENE-041212-73
Name
24-dehydrocholesterol reductase
Symbol
dhcr24 Nomenclature History
Previous Names
  • zgc:101638
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have delta24(24-1) sterol reductase activity. Predicted to be involved in steroid metabolic process. Predicted to localize to cytoplasm and membrane. Is expressed in cranial ganglion; lens; solid lens vesicle; telencephalon; and yolk syncytial layer. Human ortholog(s) of this gene implicated in lipid metabolism disorder. Orthologous to human DHCR24 (24-dehydrocholesterol reductase).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dhcr24 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Desmosterolosis 602398
Associated With dhcr24 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR006094 FAD linked oxidase, N-terminal
Domain IPR016166 FAD-binding domain, PCMH-type
Family IPR040165 Delta(24)-sterol reductase
Homologous_superfamily IPR016169 FAD-binding, type PCMH, subdomain 2
Homologous_superfamily IPR036318 FAD-binding, type PCMH-like superfamily
Domain Details Per Protein
Protein Length Delta(24)-sterol reductase FAD-binding domain, PCMH-type FAD-binding, type PCMH-like superfamily FAD-binding, type PCMH, subdomain 2 FAD linked oxidase, N-terminal
UniProtKB:A7E2N4 380
UniProtKB:Q5PRC9 516
UniProtKB:F8W2X8 380
UniProtKB:F1QUM4 516
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations