Gene

iqcb1

ID
ZDB-GENE-041212-47
Name
IQ motif containing B1
Symbol
iqcb1 Nomenclature History
Previous Names
  • nphp5 (1)
  • zgc:101792
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have calmodulin binding activity. Involved in opsin transport and pronephros development. Human ortholog(s) of this gene implicated in Leber congenital amaurosis; Senior-Loken syndrome; nephronophthisis; and retinitis pigmentosa 3. Orthologous to human IQCB1 (IQ motif containing B1).
Genome Resources
Note
None
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
3 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With iqcb1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Senior-Loken syndrome Alliance Senior-Loken syndrome 5 609254
Associated With iqcb1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Family IPR028765 IQ calmodulin-binding motif-containing protein 1
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Domain Details Per Protein
Protein Length IQ calmodulin-binding motif-containing protein 1 IQ motif, EF-hand binding site P-loop containing nucleoside triphosphate hydrolase
UniProtKB:A8KC58 295
UniProtKB:A0A0R4IC62 464
UniProtKB:F1QYF8 586
UniProtKB:A0A0G2KKU5 421
UniProtKB:Q5PRA5 595
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations