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Gene

iqsec3a

ID
ZDB-GENE-041210-343
Name
IQ motif and Sec7 domain ArfGEF 3a
Symbol
iqsec3a Nomenclature History
Previous Names
  • si:ch211-15l13.1 (1)
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to be involved in actin cytoskeleton organization. Predicted to act upstream of or within regulation of ARF protein signal transduction. Predicted to be located in cytoplasm. Is expressed in central nervous system and neurons. Orthologous to human IQSEC3 (IQ motif and Sec7 domain ArfGEF 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
4 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With iqsec3a Human Ortholog
No data available
Associated With iqsec3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000048 IQ motif, EF-hand binding site
Domain IPR000904 Sec7 domain
Domain IPR033742 IQ motif and SEC7 domain-containing protein, PH domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Homologous_superfamily IPR023394 Sec7, C-terminal domain superfamily
Homologous_superfamily IPR035999 Sec7 domain superfamily
Domain Details Per Protein
Protein Length IQ motif and SEC7 domain-containing protein, PH domain IQ motif, EF-hand binding site PH-like domain superfamily Sec7, C-terminal domain superfamily Sec7 domain Sec7 domain superfamily
UniProtKB:A0A0R4IUT7 1277
UniProtKB:A0A2R8RWG7 659
UniProtKB:A0A2R8Q8B4 317
UniProtKB:A0A2R8QKA7 636
UniProtKB:A0A2R8Q3P9 700
UniProtKB:A0A0R4IIU3 791
UniProtKB:A0A2R8Q8B8 583
UniProtKB:Q5PNQ8 602
UniProtKB:A0A2R8QKS7 676
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations