Gene

tfec

ID
ZDB-GENE-041210-21
Name
transcription factor EC
Symbol
tfec Nomenclature History
Previous Names
  • si:ch211-238e6.5
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in definitive hemopoiesis; hematopoietic stem cell homeostasis; and hematopoietic stem cell proliferation. Predicted to localize to nucleus. Is expressed in several structures, including extension; eye; immature eye; intermediate cell mass of mesoderm; and neural crest. Orthologous to human TFEC (transcription factor EC).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 5 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With tfec Human Ortholog
No data available
Associated With tfec Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Domain IPR021802 MiT/TFE transcription factors, C-terminal
Domain IPR031867 MiT/TFE transcription factors, N-terminal
Family IPR024101 Transcription factor EC
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
Domain Details Per Protein
Protein Length Helix-loop-helix DNA-binding domain superfamily MiT/TFE transcription factors, C-terminal MiT/TFE transcription factors, N-terminal Myc-type, basic helix-loop-helix (bHLH) domain Transcription factor EC
UniProtKB:Q1JQ62 396
UniProtKB:A0A0R4IX50 396
UniProtKB:G5CIM5 234
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations