Gene

lamb1b

ID
ZDB-GENE-041210-197
Name
laminin, beta 1b
Symbol
lamb1b Nomenclature History
Previous Names
  • si:dkey-183c16.5
Type
protein_coding_gene
Location
Chr: 4 Mapping Details/Browsers
Description
Predicted to have extracellular matrix structural constituent and integrin binding activity. Predicted to be involved in several processes, including basement membrane assembly; cell migration; and substrate adhesion-dependent cell spreading. Predicted to localize to laminin complex. Human ortholog(s) of this gene implicated in autistic disorder and lissencephaly. Is expressed in fin; median fin fold; nervous system; and notochord. Orthologous to human LAMB1 (laminin subunit beta 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With lamb1b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
lissencephaly 5 Alliance Lissencephaly 5 615191
Associated With lamb1b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000742 EGF-like domain
Domain IPR002049 Laminin EGF domain
Domain IPR008211 Laminin, N-terminal
Domain IPR013015 Laminin IV type B
Homologous_superfamily IPR038684 Laminin, N-terminal domain superfamily
Domain Details Per Protein
Protein Length EGF-like domain Laminin EGF domain Laminin IV type B Laminin, N-terminal Laminin, N-terminal domain superfamily
UniProtKB:F1QEB6 1714
UniProtKB:A0A2R8QMV5 1771
UniProtKB:F1REL9 1767
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations