ZFIN ID: ZDB-GENE-041210-171
Gene Name: suppressor of cytokine signaling 2
Gene Symbol: socs2
Sequence Ontology ID : SO:0000704

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Previous Name: si:dkey-202b22.1

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(Including Attributions)
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have 1-phosphatidylinositol-3-kinase regulator activity; predicted to be involved in negative regulation of insulin receptor signaling pathway and phosphatidylinositol phosphorylation;  ...
GENE EXPRESSION
All Expression Data: Fig. 5 from Lewis et al., 2014
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb30 Indel Unknown Unknown TALEN
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • ihb34 Small Deletion Unknown Unknown TALEN
  • China Zebrafish Resource Center (CZRC, ZKO consortium) (order this)
  • sa13561 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH socs2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH socs2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Cellular Component cytoplasm (more)
    Molecular Function insulin-like growth factor receptor binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000980 (1)
  • InterPro:IPR001496 (1)
  • InterPro:IPR028410 (1)
  • InterPro:IPR035862 (1)
  • InterPro:IPR036036 (1)
  • InterPro:IPR036860 (1)
  • PROSITE:PS50001 (1)
  • PROSITE:PS50225 (1)
  • Pfam:PF00017 (1)
  • Pfam:PF07525 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA socs2-201 (1) 1791
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM socs2 No data available
    MARKER RELATIONSHIPS
    socs2Contained in: [BAC] DKEY-202B22 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001114550 (1) 594bp
    Genomic GenBank:BX649398 (1) 166156bp
    Select Tool
    Polypeptide UniProtKB:B0EVP5 (1) 197aa
    Sequence Clusters UniGene:150021 (1)
    Sequence Information (all 15)
    OTHER socs2 GENE PAGES
  • Alliance (1)
  • Gene:562062 (1)
  • VEGA:OTTDARG00000008129 (1)
  • Ensembl(GRCz11):ENSDARG00000045557 (2)
  • ORTHOLOGY for socs2 (Chr: 4)
    CITATIONS (25)