ZFIN ID: ZDB-GENE-041210-171
Gene Name: suppressor of cytokine signaling 2
Gene Symbol: socs2    Nomenclature History

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Previous Name: si:dkey-202b22.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have 1-phosphatidylinositol-3-kinase regulator activity. Predicted to be involved in phosphatidylinositol phosphorylation. Predicted to localize to phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in endometrial cancer and ovarian carcinoma. Orthologous to human SOCS2 (suppressor of cytokine signaling 2).
Genome Resources: Alliance (1),  Gene:562062 (1), 
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ihb30 Indel Unknown Unknown TALEN
  • China Zebrafish Resource Center (CZRC) (order this)
  • ihb34 Small Deletion Unknown Unknown TALEN
  • China Zebrafish Resource Center (CZRC) (order this)
  • sa13561 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH socs2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH socs2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intracellular signal transduction (more)
    Cellular Component cytoplasm (more)
    Molecular Function insulin-like growth factor receptor binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA socs2-201 (1)    Ensembl 1791
    Browsers: NCBI
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM socs2 No data available
    MARKER RELATIONSHIPS
    socs2 Contained in: [BAC] DKEY-202B22 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001114550 (1) 594 nt
    Genomic GenBank:BX649398 (1) 166156 nt
    Select Tool
    Polypeptide UniProtKB:B0EVP5 (1) 197 aa
    Sequence Information (all 14)
    ORTHOLOGY for socs2 ( Chr: 4 )
    CITATIONS (25)