ZFIN ID: ZDB-GENE-041210-167
Gene Name: plakophilin 2
Gene Symbol: pkp2
Previous Name: si:ch211-11c20.1
Location: Chr: 4   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from Moriarty et al., 2008
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  epidermis, heart, neuroepithelial cell, whole organism
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-pkp2 (1)
PHENOTYPE
Data: 4 figures from Moriarty et al., 2012
Observed in: atrium, blood, cardiac ventricle, heart cell-cell junction (all 10) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Arrhythmogenic right ventricular dysplasia 9 609040
GENE ONTOLOGY
Ontology GO Term
Biological Process desmosome organization (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000225 (1)
  • InterPro:IPR011989 (1)
  • InterPro:IPR016024 (1)
  • InterPro:IPR028435 (1)
  • PROSITE:PS50176 (1)
  • Pfam:PF00514 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pkp2-001 (1) 1740
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM pkp2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    pkp2 Contained in: [BAC] CH211-11C20 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001113433 (1) 2824 bp
    Genomic GenBank:BX001012 (1) 158481 bp
    Select Tool
    Polypeptide UniProtKB:B0BF33 (1) 815 aa
    Sequence Clusters UniGene:83512 (1)
    Sequence Information (all 10)
    OTHER pkp2 GENE PAGES
  • Gene:568060 (1)
  • VEGA:OTTDARG00000008109 (1)
  • Ensembl(Zv9):ENSDARG00000023026 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish pkp2 4  
    Human PKP2 12 (12p11)
  • OMIM:602861
  • Gene:5318
  • Orthology Details
    CITATIONS (11)