ZFIN ID: ZDB-GENE-041210-167
Gene Name: plakophilin 2
Gene Symbol: pkp2
Previous Name: si:ch211-11c20.1
Location: Chr: 4 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Cleavage:64-cell (2.0h-2.25h) to Adult (90d-730d, breeding adult)
  epidermis, heart, neuroepithelial cell, whole organism
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents: MO1-pkp2 (1)
PHENOTYPE
Data: 4 figures from Moriarty et al., 2012
Observed in: atrium, blood, cardiac ventricle, heart cell-cell junction (all 10) expand
DISEASE ASSOCIATED WITH pkp2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
arrhythmogenic right ventricular dysplasia 9 Arrhythmogenic right ventricular dysplasia 9 609040
GENE ONTOLOGY
Ontology GO Term
Biological Process desmosome organization (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000225 (1)
  • InterPro:IPR011989 (1)
  • InterPro:IPR016024 (1)
  • InterPro:IPR028435 (1)
  • PROSITE:PS50176 (1)
  • Pfam:PF00514 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pkp2-001 (1) 1740
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pkp2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    pkp2Contained in: [BAC] CH211-11C20 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001113433 (1) 2824bp
    Genomic GenBank:BX001012 (1) 158481bp
    Select Tool
    Polypeptide UniProtKB:B0BF33 (1) 815aa
    Sequence Clusters UniGene:83512 (1)
    Sequence Information (all 9)
    OTHER pkp2 GENE PAGES
  • Gene:568060 (1)
  • VEGA:OTTDARG00000008109 (1)
  • Ensembl(GRCz10):ENSDARG00000023026 (1)
  • ORTHOLOGY for pkp2 (Chr: 4)
    Species Symbol Chromosome Accession # Evidence
    Human PKP2 12
  • Gene:5318
  • OMIM:602861
  • HGNC:9024
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (12)