ZFIN ID: ZDB-GENE-041210-125
Gene Name: glutamate receptor interacting protein 1
Gene Symbol: grip1    Nomenclature History

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Previous Names: si:dkey-244b23.1, si:dkey-6a5.1

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 4 Mapping Details/Browsers
Description: Predicted to have glucocorticoid receptor binding activity. Predicted to be involved in neurotransmitter receptor transport, endosome to postsynaptic membrane. Is expressed in brain; eye; median fin fold; and somite. Human ortholog(s) of this gene implicated in Fraser syndrome 3. Orthologous to human GRIP1 (glutamate receptor interacting protein 1).
Genome Resources: Alliance (1),  Gene:558006 (1),  Ensembl(GRCz11):ENSDARG00000015053 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la024414Tg Transgenic Insertion Unknown Unknown DNA
la024415Tg Transgenic Insertion Unknown Unknown DNA
mn0078Gt Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17341 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33422 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa40251 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-grip1 N/A 1
    MO2-grip1 N/A 1
    PHENOTYPE
    Data: Table 1 from Clark et al., 2011
    Observed in:
    DISEASE ASSOCIATED WITH grip1 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Fraser syndrome 3 Alliance Fraser syndrome 3 617667
    DISEASE ASSOCIATED WITH grip1 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dendrite development (more)
    Molecular Function signaling receptor complex adaptor activity (more)
    GO Terms (all 4)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA grip1-201 (1)    Ensembl 3610
    ncRNA grip1-002 (1)    Ensembl 830
    grip1-003 (1)    Ensembl 586
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM grip1 No data available
    MARKER RELATIONSHIPS
    grip1 Contained in: [BAC] DKEY-6A5 (1) (order this), DKEY-147I20 (1) (order this), DKEY-244B23 (1) (order this)
    grip1 Encodes: [cDNA] MGC:198319 (1), MGC:198321 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001044851 (1) 3432 nt
    Genomic GenBank:BX119963 (1) 229125 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0R4IVS6 (1) 1156 aa
    Sequence Information (all 50)
    ORTHOLOGY for grip1 ( Chr: 4 )
    CITATIONS (35)