ZFIN ID: ZDB-GENE-041124-3
Gene Name: exostosin glycosyltransferase 2
Gene Symbol: ext2
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: ext2a (1), dackel, dak, fc14g07, wu:fc14g07 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 7 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity; involved in several processes, including animal organ development, generation of neurons, and glycoprotein  ...
GENE EXPRESSION
All Expression Data: Fig. 5 from Lee et al., 2004
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Pharyngula:Prim-25 (36.0h-42.0h)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE
Data: 54 figures from 18 publications
Observed in:
DISEASE ASSOCIATED WITH ext2 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
hereditary multiple exostoses Exostoses, multiple, type 2 133701
?Seizures, scoliosis, and macrocephaly syndrome 616682
DISEASE ASSOCIATED WITH ext2 VIA EXPERIMENTAL MODELS
Human Disease Fish Conditions Citations
hereditary multiple exostoses ext2to273b/to273b standard conditions Wiweger et al., 2014
GENE ONTOLOGY
Ontology GO Term
Biological Process chondroitin sulfate proteoglycan biosynthetic process (more)
Cellular Component integral component of membrane (more)
Molecular Function N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity (more)
GO Terms (all 26)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR004263 (1)
  • InterPro:IPR015338 (1)
  • InterPro:IPR027673 (1)
  • InterPro:IPR029044 (1)
  • InterPro:IPR040911 (1)
  • Pfam:PF03016 (1)
  • Pfam:PF09258 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ext2-001 (1) 3172
    ncRNA ext2-002 (1) 784
    ext2-003 (1) 667
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ext2
    MARKER RELATIONSHIPS
    ext2Contained in: [BAC] CH211-107P11 (1) (order this)
    ext2Encodes: [EST] fc14g07
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001008400 (1) 3195bp
    Genomic GenBank:BX510305 (1) 156938bp
    Select Tool
    Polypeptide UniProtKB:F1QUC2 (1) 719aa
    Sequence Clusters UniGene:37595 (1)
    Sequence Information (all 11)
    OTHER ext2 GENE PAGES
  • Alliance (1)
  • Gene:493780 (1)
  • VEGA:OTTDARG00000020136 (1)
  • Ensembl(GRCz11):ENSDARG00000056648 (2)
  • ORTHOLOGY for ext2 (Chr: 7)
    CITATIONS (53)