Gene
aicda
- ID
- ZDB-GENE-041122-2
- Name
- activation-induced cytidine deaminase
- Symbol
- aicda Nomenclature History
- Previous Names
-
- aid (1)
- Type
- protein_coding_gene
- Location
- Chr: 16 Mapping Details/Browsers
- Description
- Exhibits cytidine deaminase activity. Involved in somatic cell DNA recombination. Predicted to localize to cytoplasm and nucleus. Is expressed in head and intestine. Human ortholog(s) of this gene implicated in hyperimmunoglobulin syndrome and immunodeficiency with hyper-IgM type 2. Orthologous to human AICDA (activation induced cytidine deaminase).
- Genome Resources
- Note
- None
- All Expression Data
- 4 figures from Rai et al., 2010
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
---|---|---|---|
immunodeficiency with hyper-IgM type 2 | Alliance | Immunodeficiency with hyper-IgM, type 2 | 605258 |
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | APOBEC/CMP deaminase, zinc-binding | Cytidine and deoxycytidylate deaminase domain | Cytidine deaminase-like |
---|---|---|---|---|
UniProtKB:Q5YF88
|
210 | |||
UniProtKB:B3DGZ0
|
210 |
Interactions and Pathways
No data available
Plasmids
No data available
- Gene Tree
- Ensembl