Gene

aicda

ID
ZDB-GENE-041122-2
Name
activation-induced cytidine deaminase
Symbol
aicda Nomenclature History
Previous Names
  • aid (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Exhibits cytidine deaminase activity. Involved in somatic cell DNA recombination. Predicted to localize to cytoplasm and nucleus. Is expressed in head and intestine. Human ortholog(s) of this gene implicated in hyperimmunoglobulin syndrome and immunodeficiency with hyper-IgM type 2. Orthologous to human AICDA (activation induced cytidine deaminase).
Genome Resources
Note
None
Expression
All Expression Data
4 figures from Rai et al., 2010
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With aicda Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency with hyper-IgM type 2 Alliance Immunodeficiency with hyper-IgM, type 2 605258
Associated With aicda Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR016192 APOBEC/CMP deaminase, zinc-binding
Domain IPR002125 Cytidine and deoxycytidylate deaminase domain
Homologous_superfamily IPR016193 Cytidine deaminase-like
Domain Details Per Protein
Protein Length APOBEC/CMP deaminase, zinc-binding Cytidine and deoxycytidylate deaminase domain Cytidine deaminase-like
UniProtKB:Q5YF88 210
UniProtKB:B3DGZ0 210
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations