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ZIRC
ZFIN ID: ZDB-GENE-041122-2
Gene Name: activation-induced cytidine deaminase
Gene Symbol: aicda    Nomenclature History

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Previous Name: aid (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Exhibits cytidine deaminase activity. Involved in somatic cell DNA recombination. Predicted to localize to the cytoplasm and nucleus. Human ortholog(s) of this gene implicated in hyperimmunoglobulin syndrome and immunodeficiency with hyper-IgM type 2. Is expressed in head and intestine. Orthologous to human AICDA (activation induced cytidine deaminase).
Genome Resources: Alliance (1),  Gene:493784 (1),  Ensembl(GRCz11):ENSDARG00000015734 (1)
GENE EXPRESSION
All Expression Data: 4 figures from Rai et al., 2010
Wild-type Stages, Structures: Hatching:Long-pec (48.0h-60.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-aicda N/A 3
PHENOTYPE No data available
DISEASE ASSOCIATED WITH aicda HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
immunodeficiency with hyper-IgM type 2 Alliance Immunodeficiency with hyper-IgM, type 2 605258
DISEASE ASSOCIATED WITH aicda VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process somatic cell DNA recombination (more)
Cellular Component nucleus (more)
Molecular Function cytidine deaminase activity (more)
GO Terms (all 10)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA aicda-201 (1)    Ensembl 869
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM aicda No data available
MARKER RELATIONSHIPS
aicda Contained in: [BAC] DKEY-38O19 (1) (order this)
[Fosmid] CH1073-443O9 (1) (order this)
aicda Encodes: [cDNA] MGC:193818 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001008403 (1) 889 bp
Genomic GenBank:CR848818 (1) 208738 bp Blast at MegaBLAST
Polypeptide UniProtKB:B3DGZ0 (1) 210 aa
Sequence Clusters UniGene:92887 (1)
Sequence Information (all 13)
ORTHOLOGY for aicda ( Chr: 16 )
CITATIONS (29)