ZFIN ID: ZDB-GENE-041121-1
Gene Name: growth factor receptor-bound protein 2a
Gene Symbol: grb2a    Nomenclature History

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Previous Name: zgc:103549

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to localize to nucleoplasm. Human ortholog(s) of this gene implicated in breast cancer; prostate adenocarcinoma; and prostate cancer. Orthologous to human GRB2 (growth factor receptor bound protein 2).
Genome Resources: Alliance (1),  Gene:493609 (1),  Ensembl(GRCz11):ENSDARG00000105276 (1)
GENE EXPRESSION
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa26721 Point Mutation Unknown Unknown ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH grb2a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH grb2a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process peptidyl-tyrosine phosphorylation (more)
Cellular Component nucleoplasm (more)
GO Terms (all 2)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA grb2a-201 (1)    Ensembl 1497
grb2a-202 (1)    Ensembl 645
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM grb2a No data available
MARKER RELATIONSHIPS
grb2a Contained in: [BAC] CH211-260P11 (1)
grb2a Encodes: [cDNA] MGC:103549 (1), MGC:192215 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001007769 (1) 1449 nt
Genomic GenBank:CR387927 (1) 149672 nt
Select Tool
Polypeptide UniProtKB:Q5RKN6 (1) 217 aa
Sequence Information (all 13)
ORTHOLOGY for grb2a ( Chr: 6 )
CITATIONS (17)