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ZIRC
ZFIN ID: ZDB-GENE-041116-2
Gene Name: DMRT-like family A2
Gene Symbol: dmrta2    Nomenclature History

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Previous Name: Dmrt5 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity; metal ion binding activity; and sequence-specific DNA binding activity. Involved in corticotropin hormone secreting cell differentiation and telencephalon development. Predicted to localize to the nucleus. Is expressed in central nervous system; ectoderm; endocrine system; and neural keel. Orthologous to human DMRTA2 (DMRT like family A2).
Genome Resources: Alliance (1),  Gene:474350 (1),  Ensembl(GRCz11):ENSDARG00000039412 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ha2 Point Mutation Unknown Missense ENU
sa13156 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-dmrta2 N/A 1
    MO2-dmrta2 N/A 1
    MO3-dmrta2 N/A 1
    DISEASE ASSOCIATED WITH dmrta2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dmrta2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process corticotropin hormone secreting cell differentiation (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 9)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA dmrta2-201 (1)    Ensembl 1419
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM dmrta2
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(dmrta2:RTTA,CMV:MYC-dmrta2_R106Q) CMVdmrta2 dmrta2MYCRTTA Danio rerio 1 1
    MARKER RELATIONSHIPS
    dmrta2 Contained in: [BAC] CH73-349N16 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007064 (1) 1419 bp
    Genomic GenBank:CU467870 (1) 89448 bp
    Select Tool
    Polypeptide UniProtKB:B8JLF1 (1) 440 aa
    Sequence Clusters UniGene:92895 (1)
    Sequence Information (all 10)
    ORTHOLOGY for dmrta2 ( Chr: 8 )
    CITATIONS (27)