Gene
vtnb
- ID
- ZDB-GENE-041116-1
- Name
- vitronectin b
- Symbol
- vtnb Nomenclature History
- Previous Names
-
- vtn
- Type
- protein_coding_gene
- Location
- Chr: 21 Mapping Details/Browsers
- Description
- Predicted to have polysaccharide binding activity and scavenger receptor activity. Predicted to be involved in immune response. Predicted to localize to extracellular region. Is expressed in hypothalamus; liver; liver primordium; and yolk syncytial layer. Human ortholog(s) of this gene implicated in Churg-Strauss syndrome; granulomatosis with polyangiitis; and thrombosis. Orthologous to human VTN (vitronectin).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 14 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- IMAGE:6907751 (6 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Domain | IPR000585 | Hemopexin-like domain |
| Domain | IPR001212 | Somatomedin B domain |
| Domain | IPR020436 | Somatomedin B domain, chordata |
| Family | IPR051298 | Heme transport and cell adhesion protein |
| Homologous_superfamily | IPR036024 | Somatomedin B-like domain superfamily |
| Homologous_superfamily | IPR036375 | Hemopexin-like domain superfamily |
| Repeat | IPR018487 | Hemopexin-like repeats |
Domain Details Per Protein
| Protein | Length | Heme transport and cell adhesion protein | Hemopexin-like domain | Hemopexin-like domain superfamily | Hemopexin-like repeats | Somatomedin B domain | Somatomedin B domain, chordata | Somatomedin B-like domain superfamily |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:F1Q5D8
|
449 | |||||||
|
UniProtKB:A7E2Q3
|
469 |
Interactions and Pathways
No data available
Plasmids
No data available