Gene

vtnb

ID
ZDB-GENE-041116-1
Name
vitronectin b
Symbol
vtnb Nomenclature History
Previous Names
  • vtn
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to have polysaccharide binding activity and scavenger receptor activity. Predicted to be involved in immune response. Human ortholog(s) of this gene implicated in Churg-Strauss syndrome; granulomatosis with polyangiitis; and thrombosis. Is expressed in hypothalamus; liver; liver primordium; and yolk syncytial layer. Orthologous to human VTN (vitronectin).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
14 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With vtnb Human Ortholog
No data available
Associated With vtnb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000585 Hemopexin-like domain
Domain IPR001212 Somatomedin B domain
Homologous_superfamily IPR036024 Somatomedin B-like domain superfamily
Homologous_superfamily IPR036375 Hemopexin-like domain superfamily
Repeat IPR018487 Hemopexin-like repeats
Domain Details Per Protein
Protein Length Hemopexin-like domain Hemopexin-like domain superfamily Hemopexin-like repeats Somatomedin B domain Somatomedin B-like domain superfamily
UniProtKB:A7E2Q3 469
UniProtKB:F1Q5D8 449
UniProtKB:Q7SXJ7 463
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations