Gene

haao

ID
ZDB-GENE-041114-89
Name
3-hydroxyanthranilate 3,4-dioxygenase
Symbol
haao Nomenclature History
Previous Names
  • zgc:103585
Type
protein_coding_gene
Location
Chr: 13 Mapping Details/Browsers
Description
Predicted to have 3-hydroxyanthranilate 3,4-dioxygenase activity and ferrous iron binding activity. Predicted to be involved in 'de novo' NAD biosynthetic process from tryptophan and quinolinate biosynthetic process. Predicted to localize to cytoplasm. Is expressed in intestinal bulb and liver. Orthologous to human HAAO (3-hydroxyanthranilate 3,4-dioxygenase).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With haao Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Vertebral, cardiac, renal, and limb defects syndrome 1 617660
Associated With haao Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR010329 3-hydroxyanthranilic acid dioxygenase
Family IPR016700 3-hydroxyanthranilate 3, 4-dioxygenase, metazoan
Homologous_superfamily IPR011051 RmlC-like cupin domain superfamily
Homologous_superfamily IPR014710 RmlC-like jelly roll fold
Domain Details Per Protein
Protein Length 3-hydroxyanthranilate 3, 4-dioxygenase, metazoan 3-hydroxyanthranilic acid dioxygenase RmlC-like cupin domain superfamily RmlC-like jelly roll fold
UniProtKB:A0A0R4IS69 273
UniProtKB:B2GQ93 287
UniProtKB:F1QYC7 287
UniProtKB:Q5U3F8 287
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations