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Gene

ftsj1

ID
ZDB-GENE-041114-83
Name
FtsJ RNA 2'-O-methyltransferase 1
Symbol
ftsj1 Nomenclature History
Previous Names
  • fb17g12
  • wu:fb17g12
  • zgc:101831
Type
protein_coding_gene
Location
Chr: 21 Mapping Details/Browsers
Description
Predicted to enable tRNA methyltransferase activity. Predicted to be involved in cytoplasmic translation and tRNA methylation. Predicted to act upstream of or within methylation and tRNA processing. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in non-syndromic X-linked intellectual disability 9. Orthologous to human FTSJ1 (FtsJ RNA 2'-O-methyltransferase 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ftsj1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
non-syndromic X-linked intellectual disability 9 Alliance Intellectual developmental disorder, X-linked 9 309549
Associated With ftsj1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR002877 Ribosomal RNA methyltransferase FtsJ domain
Family IPR015507 Ribosomal RNA large subunit methyltransferase E
Family IPR028590 tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Domain Details Per Protein
Protein Length Ribosomal RNA large subunit methyltransferase E Ribosomal RNA methyltransferase FtsJ domain S-adenosyl-L-methionine-dependent methyltransferase tRNA (cytidine(32)/guanosine(34)-2-O)-methyltransferase, Trm7
UniProtKB:E9QJK6 127
UniProtKB:A8E5E3 323
UniProtKB:F1QDU3 323
UniProtKB:F8W2U2 64
UniProtKB:Q5U3P4 323
UniProtKB:E9QIQ0 167
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations