ZFIN ID: ZDB-GENE-041114-26
Gene Name: guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type
Gene Symbol: gnal    Nomenclature History

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Previous Names: GNAL1 (1), Galpha olf2 (1), Golf1 (1), zgc:103521

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have G protein-coupled receptor binding activity; G-protein beta/gamma-subunit complex binding activity; and GTPase activity. Predicted to be involved in adenylate cyclase-activating dopamine receptor signaling pathway and sensory perception of chemical stimulus. Predicted to localize to heterotrimeric G-protein complex. Is expressed in brain; gill; head; and peripheral olfactory organ. Human ortholog(s) of this gene implicated in dystonia 25. Orthologous to human GNAL (G protein subunit alpha L).
Genome Resources: Alliance (1),  Gene:492467 (1),  Ensembl(GRCz11):ENSDARG00000045415 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023093Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa1505 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH gnal HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    dystonia 25 Alliance Dystonia 25 615073
    DISEASE ASSOCIATED WITH gnal VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process G protein-coupled receptor signaling pathway (more)
    Cellular Component heterotrimeric G-protein complex (more)
    Molecular Function G-protein beta/gamma-subunit complex binding (more)
    GO Terms (all 12)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA gnal-202 (1)    Ensembl 1187
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM gnal No data available
    MARKER RELATIONSHIPS
    gnal Contained in: [BAC] CH211-203G10 (1), CH211-227I15 (1), DKEY-204M11 (1) (order this)
    gnal Encodes: [cDNA] MGC:103521 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001007339 (1) 1778 nt
    Genomic GenBank:CR318624 (1) 170084 nt
    Select Tool
    Polypeptide UniProtKB:F1RE11 (1) 379 aa
    Sequence Information (all 13)
    ORTHOLOGY for gnal ( Chr: 24 )
    CITATIONS (32)