ZFIN ID: ZDB-GENE-041114-20
Gene Name: adaptor related protein complex 1 subunit mu 2
Gene Symbol: ap1m2    Nomenclature History

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Previous Name: zgc:103537

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have clathrin adaptor activity. Involved in animal organ development; digestive tract development; and post-Golgi vesicle-mediated transport. Predicted to localize to clathrin-coated vesicle and intracellular membrane-bounded organelle. Is expressed in several structures, including digestive system; eye; heart; intestinal bulb primordium; and pleuroperitoneal region. Orthologous to human AP1M2 (adaptor related protein complex 1 subunit mu 2).
Genome Resources: Alliance (1),  Gene:403021 (1),  Ensembl(GRCz11):ENSDARG00000096454 (2)
GENE EXPRESSION
All Expression Data: 4 figures from 3 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:103537]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la015938Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa20601 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-ap1m2 N/A 1
    MO2-ap1m2 N/A 1
    MO3-ap1m2 N/A 1
    DISEASE ASSOCIATED WITH ap1m2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ap1m2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process post-Golgi vesicle-mediated transport (more)
    Cellular Component clathrin adaptor complex (more)
    Molecular Function clathrin adaptor activity (more)
    GO Terms (all 16)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ap1m2-201 (1)    Ensembl 1776
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ap1m2 No data available
    MARKER RELATIONSHIPS
    ap1m2 Contained in: [Fosmid] ZFOS-323E3 (1)
    ap1m2 Encodes: [cDNA] MGC:103537 (1), MGC:192655 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_205714 (1) 1688 nt
    Genomic GenBank:CU693486 (1) 42264 nt
    Select Tool
    Polypeptide UniProtKB:E7FBU8 (1) 1052 aa
    Sequence Information (all 19)
    ORTHOLOGY for ap1m2 ( Chr: 6 )
    CITATIONS (28)