ZFIN ID: ZDB-GENE-041114-190
Gene Name: ubiquitin protein ligase E3A
Gene Symbol: ube3a
Previous Names: im:7140733, zgc:92173 (1)
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7140733]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  unspecified
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025542Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9479 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ube3a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Angelman syndrome Angelman syndrome 105830
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process ubiquitin-dependent protein catabolic process (more)
    Cellular Component cytoplasm (more)
    Molecular Function ligase activity (more)
    GO Terms (all 8)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000569 (1)
  • InterPro:IPR017134 (1)
  • InterPro:IPR032353 (1)
  • PROSITE:PS50237 (1)
  • Pfam:PF00632 (1)
  • Pfam:PF16558 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ube3a-001 (1) 4104
    ncRNA ube3a-002 (1) 865
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ube3a No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ube3aContained in: [BAC] DKEY-22G9 (1) (order this)
    ube3aEncodes: [EST] IMAGE:7140733 (1) (order this)
    [cDNA] MGC:92173 (1) (order this), MGC:174322 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007318 (1) 4093bp
    Genomic GenBank:CR388007 (1) 221983bp Blast at MegaBLAST
    Polypeptide UniProtKB:F1R4B5 (1) 857aa
    Sequence Clusters UniGene:37442 (1)
    Sequence Information (all 19)
    OTHER ube3a GENE PAGES
  • Gene:792398 (1)
  • VEGA:OTTDARG00000022014 (1)
  • Ensembl(GRCz10):ENSDARG00000055737 (1)
  • ORTHOLOGY for ube3a (Chr: 6)
    Species Symbol Chromosome Accession # Evidence
    Human UBE3A 15
  • Gene:7337
  • OMIM:601623
  • HGNC:12496
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Ube3a 7
  • MGI:105098
  • Gene:22215
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (20)