Gene

ppm1bb

ID
ZDB-GENE-041114-185
Name
protein phosphatase, Mg2+/Mn2+ dependent, 1Bb
Symbol
ppm1bb Nomenclature History
Previous Names
  • ppm1a
  • fc18g04
  • wu:fc18g04
  • zgc:92329
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have magnesium-dependent protein serine/threonine phosphatase activity. Involved in negative regulation of transforming growth factor beta receptor signaling pathway. Predicted to localize to cytosol and nucleus. Orthologous to human PPM1B (protein phosphatase, Mg2+/Mn2+ dependent 1B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Lin et al., 2006
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ppm1bb Human Ortholog
No data available
Associated With ppm1bb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Binding_site IPR000222 PPM-type phosphatase, divalent cation binding
Domain IPR001932 PPM-type phosphatase-like domain
Domain IPR012911 Protein serine/threonine phosphatase 2C, C-terminal
Homologous_superfamily IPR036457 PPM-type phosphatase-like domain superfamily
Homologous_superfamily IPR036580 Phosphatase 2C, C-terminal domain superfamily
Domain Details Per Protein
Protein Length Phosphatase 2C, C-terminal domain superfamily PPM-type phosphatase, divalent cation binding PPM-type phosphatase-like domain PPM-type phosphatase-like domain superfamily Protein serine/threonine phosphatase 2C, C-terminal
UniProtKB:A0A8M2B2A8 475
UniProtKB:Q5U386 382
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations