ZFIN ID: ZDB-GENE-041114-174
Gene Name: ceroid-lipofuscinosis, neuronal 3
Gene Symbol: cln3
Previous Name: zgc:92244 (1)
Location: Chr: 3   Details
Nomenclature History
GENE EXPRESSION
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92244]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
  whole organism
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS

Allele Type Mutagen Suppliers
sa20092 Point Mutation ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH cln3 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
neuronal ceroid lipofuscinosis Ceroid lipofuscinosis, neuronal, 3 204200
GENE ONTOLOGY
Ontology GO Term
Biological Process arginine transport (more)
Cellular Component integral component of membrane (more)
GO Terms (all 9)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003492 (1)
  • InterPro:IPR018460 (1)
  • InterPro:IPR020846 (1)
  • Pfam:PF02487 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cln3-001 (1) 1873
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM cln3 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    cln3 Contained in: [BAC] CH211-198P11 (1) (order this)
    cln3 Encodes: [cDNA] MGC:92244 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007306 (1) 1858 bp
    Genomic GenBank:BX537342 (1) 195436 bp
    Select Tool
    Polypeptide UniProtKB:Q5U392 (1) 446 aa
    Sequence Clusters UniGene:79095 (1)
    Sequence Information (all 8)
    OTHER cln3 GENE PAGES
  • Gene:492340 (1)
  • VEGA:OTTDARG00000021847 (1)
  • Ensembl(Zv9):ENSDARG00000037865 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish cln3 3  
    Human CLN3 16 (16p12.1)
  • OMIM:607042
  • Gene:1201
  • Mouse Cln3 7 ( 69.16 cM)
  • MGI:107537
  • Gene:12752
  • Orthology Details
    CITATIONS (17)