ZFIN ID: ZDB-GENE-041114-174
Gene Name: ceroid-lipofuscinosis, neuronal 3
Gene Symbol: cln3
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:92244 (1)

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [MGC:92244]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Day 4 (96.0h-120.0h)
  brain, central nervous system, cerebellum, midbrain hindbrain boundary (all 5) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20092 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-cln3 (1), MO2-cln3 (1)
    PHENOTYPE
    Data: 8 figures from Wager et al., 2016
    Observed in: apoptotic process, axon extension, brain astrocyte, brain axon (all 30) expand
    DISEASE ASSOCIATED WITH cln3 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    neuronal ceroid lipofuscinosis 3 Ceroid lipofuscinosis, neuronal, 3 204200
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonogenesis (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR003492
  • InterPro:IPR018460
  • InterPro:IPR020846
  • Pfam:PF02487
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cln3-001 (1) 1873
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM cln3 No data available
    MARKER RELATIONSHIPS
    cln3Contained in: [BAC] CH211-198P11 (1) (order this)
    cln3Encodes: [cDNA] MGC:92244 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001007306 (1) 1858bp
    Genomic GenBank:BX537342 (1) 195436bp
    Select Tool
    Polypeptide UniProtKB:Q5U392 446aa
    Sequence Clusters UniGene:79095 (1)
    Sequence Information (all 9)
    OTHER cln3 GENE PAGES
  • Gene:492340 (1)
  • VEGA:OTTDARG00000021847 (1)
  • Ensembl(GRCz10):ENSDARG00000037865 (1)
  • ORTHOLOGY for cln3 (Chr: 3)
    CITATIONS (18)