Gene
thg1l
- ID
- ZDB-GENE-041114-170
- Name
- tRNA-histidine guanylyltransferase 1-like
- Symbol
- thg1l Nomenclature History
- Previous Names
-
- zgc:101609
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to enable tRNA guanylyltransferase activity. Predicted to be involved in tRNA processing. Predicted to act upstream of or within tRNA modification. Human ortholog(s) of this gene implicated in autosomal recessive spinocerebellar ataxia 28. Orthologous to human THG1L (tRNA-histidine guanylyltransferase 1 like).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:101609 (1 image)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal recessive spinocerebellar ataxia 28 | Alliance | Spinocerebellar ataxia, autosomal recessive 28 | 618800 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Thg1 C-terminal domain | tRNAHis guanylyltransferase catalytic domain | tRNAHis guanylyltransferase Thg1 | tRNAHis guanylyltransferase Thg1 superfamily |
|---|---|---|---|---|---|---|
| UniProtKB:Q5U3V1 | InterPro | 269 | ||||
| UniProtKB:A0A8M6Z217 | InterPro | 164 | ||||
| UniProtKB:A0A8M1N3E4 | InterPro | 297 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available