Gene

gnb4b

ID
ZDB-GENE-041114-167
Name
guanine nucleotide binding protein (G protein), beta polypeptide 4b
Symbol
gnb4b Nomenclature History
Previous Names
  • zgc:101614
Type
protein_coding_gene
Location
Chr: 11 Mapping Details/Browsers
Description
Predicted to have G-protein gamma-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to localize to cytoplasm and heterotrimeric G-protein complex. Is expressed in head; neuromast; and posterior lateral line primordium. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease dominant intermediate F. Orthologous to human GNB4 (G protein subunit beta 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With gnb4b Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Charcot-Marie-Tooth disease dominant intermediate F Alliance Charcot-Marie-Tooth disease, dominant intermediate F 615185
Associated With gnb4b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019775 WD40 repeat, conserved site
Domain IPR001632 G-protein, beta subunit
Domain IPR017986 WD40-repeat-containing domain
Family IPR016346 Guanine nucleotide-binding protein, beta subunit
Homologous_superfamily IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Homologous_superfamily IPR036322 WD40-repeat-containing domain superfamily
Repeat IPR001680 WD40 repeat
Repeat IPR020472 G-protein beta WD-40 repeat
Domain Details Per Protein
Protein Length G-protein, beta subunit G-protein beta WD-40 repeat Guanine nucleotide-binding protein, beta subunit WD40 repeat WD40 repeat, conserved site WD40-repeat-containing domain WD40-repeat-containing domain superfamily WD40/YVTN repeat-like-containing domain superfamily
UniProtKB:Q5U3U8 279
UniProtKB:A0A2R8RKX9 340
Transcripts
Genome Browsers
No data available
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations