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ZIRC
ZFIN ID: ZDB-GENE-041114-111
Gene Name: protein tyrosine phosphatase 4A2b
Gene Symbol: ptp4a2b    Nomenclature History

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Previous Names: PRL-2 (1), ptp4a2, fc05f09, wu:fc05f09, wu:fi84b06, zgc:101724

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have protein tyrosine phosphatase activity. Predicted to be involved in dephosphorylation. Predicted to localize to the cytoplasm and nucleus. Is expressed in several structures, including fin; gut; head; myotome; and neuromast. Orthologous to human PTP4A2 (protein tyrosine phosphatase 4A2).
Genome Resources: Alliance (1),  Gene:334483 (1),  Ensembl(GRCz11):ENSDARG00000035676 (2)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Cleavage:4-cell (1.0h-1.25h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa15070 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23568 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ptp4a2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH ptp4a2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process dephosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function phosphatase activity (more)
    GO Terms (all 6)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA ptp4a2b-201 (1)    Ensembl 2222
    ptp4a2b-203 (1)    Ensembl 816
    ncRNA ptp4a2b-003 (1) 497
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ptp4a2b No data available
    MARKER RELATIONSHIPS
    ptp4a2b Contained in: [BAC] CH211-197N10 (1) (order this)
    ptp4a2b Encodes: [EST] fc05f09, fi84b06 (1)
    [cDNA] MGC:101724 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001024098 (1) 2174 bp
    Genomic GenBank:BX957241 (1) 199001 bp
    Select Tool
    Polypeptide UniProtKB:Q5U3R3 (1) 174 aa
    Sequence Clusters UniGene:78374 (1)
    Sequence Information (all 25)
    ORTHOLOGY for ptp4a2b ( Chr: 19 )
    CITATIONS (24)