Gene

cyp3c3

ID
ZDB-GENE-041114-102
Name
cytochrome P450, family 3, subfamily c, polypeptide 3
Symbol
cyp3c3 Nomenclature History
Previous Names
  • cyp3c1l2 (1)
  • zgc:101781
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to enable steroid hydroxylase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in several structures, including adaxial cell; heart; liver; nervous system; and pleuroperitoneal region. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma; acute lymphoblastic leukemia; chronic myeloid leukemia; essential hypertension; and familial Mediterranean fever. Orthologous to several human genes including CYP3A4 (cytochrome P450 family 3 subfamily A member 4); CYP3A43 (cytochrome P450 family 3 subfamily A member 43); and CYP3A5 (cytochrome P450 family 3 subfamily A member 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With cyp3c3 Human Ortholog
No data available
Associated With cyp3c3 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017972 Cytochrome P450, conserved site
Family IPR001128 Cytochrome P450
Family IPR002401 Cytochrome P450, E-class, group I
Homologous_superfamily IPR036396 Cytochrome P450 superfamily
Domain Details Per Protein
Protein Length Cytochrome P450 Cytochrome P450, conserved site Cytochrome P450, E-class, group I Cytochrome P450 superfamily
UniProtKB:F1R2L0 482
UniProtKB:E7EY99 503
UniProtKB:Q5U3Q3 494
UniProtKB:E9QEE5 503
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations