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ZIRC
ZFIN ID: ZDB-GENE-041111-262
Gene Name: thyroid hormone receptor interactor 12
Gene Symbol: trip12    Nomenclature History

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Previous Names: im:7149446, si:ch211-272f3.4 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 18 Mapping Details/Browsers
Description: Predicted to have ubiquitin-protein transferase activity. Predicted to be involved in several processes, including cellular response to DNA damage stimulus; negative regulation of nitrogen compound metabolic process; and ubiquitin-dependent protein catabolic process. Predicted to localize to the nucleoplasm. Human ortholog(s) of this gene implicated in autosomal dominant mental retardation 49. Is expressed in myotome. Orthologous to human TRIP12 (thyroid hormone receptor interactor 12).
Genome Resources: Alliance (1),  Gene:564866 (1),  Ensembl(GRCz11):ENSDARG00000061397 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (2 images) from Thisse et al., 2004 [IMAGE:7149446]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH trip12 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal dominant mental retardation 49 Alliance Mental retardation, autosomal dominant 49 617752
DISEASE ASSOCIATED WITH trip12 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular response to DNA damage stimulus (more)
Cellular Component nucleoplasm (more)
Molecular Function ubiquitin-protein transferase activity (more)
GO Terms (all 12)
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA trip12-202 (1)    Ensembl 258
trip12-203 (1)    Ensembl 6552
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM trip12 No data available
MARKER RELATIONSHIPS
trip12 Contained in: [BAC] CH73-160P19 (1) (order this), CH211-232P17 (1) (order this), CH211-272F3 (1) (order this)
trip12 Encodes: [EST] IMAGE:7149446 (1) (order this)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001347668 (1)
Genomic GenBank:BX255879 173755 bp
Select Tool
Polypeptide UniProtKB:A0A2R8Q6F8 (1) 2111 aa
Sequence Information (all 28)
ORTHOLOGY for trip12 ( Chr: 18 )
CITATIONS (20)