Gene

elac2

ID
ZDB-GENE-041111-227
Name
elaC ribonuclease Z 2
Symbol
elac2 Nomenclature History
Previous Names
  • im:7145112
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Predicted to have 3'-tRNA processing endoribonuclease activity. Predicted to be involved in mitochondrial tRNA 3'-trailer cleavage, endonucleolytic. Predicted to localize to mitochondrion. Human ortholog(s) of this gene implicated in combined oxidative phosphorylation deficiency 17. Orthologous to human ELAC2 (elaC ribonuclease Z 2).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Thisse et al., 2004
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With elac2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
combined oxidative phosphorylation deficiency 17 Alliance Combined oxidative phosphorylation deficiency 17 615440
{Prostate cancer, hereditary, 2, susceptibility to} 614731
Associated With elac2 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001279 Metallo-beta-lactamase
Domain IPR027794 tRNase Z endonuclease
Homologous_superfamily IPR036866 Ribonuclease Z/Hydroxyacylglutathione hydrolase-like
Domain Details Per Protein
Protein Length Metallo-beta-lactamase Ribonuclease Z/Hydroxyacylglutathione hydrolase-like tRNase Z endonuclease
UniProtKB:F1QHE2 819
UniProtKB:X1WCH1 216
UniProtKB:Q4KMD9 813
UniProtKB:Q6DG69 864
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations