ZFIN ID: ZDB-GENE-041111-187
Gene Name: chromodomain helicase DNA binding protein 4a
Gene Symbol: chd4a    Nomenclature History

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Previous Names: im:7143343, si:ch211-51m24.3

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 19 Mapping Details/Browsers
Description: Predicted to have several functions, including ATP binding activity; RNA polymerase II repressing transcription factor binding activity; and histone deacetylase binding activity. Involved in fin regeneration. Predicted to localize to NuRD complex. Is expressed in blastomere and central nervous system. Orthologous to human CHD4 (chromodomain helicase DNA binding protein 4).
Genome Resources: Alliance (1),  Gene:558344 (1),  Ensembl(GRCz11):ENSDARG00000063535 (1)
GENE EXPRESSION
All Expression Data: 5 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:7143343]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Hatching:Pec-fin (60.0h-72.0h)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028079Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa3029 Point Mutation Unknown Premature Stop ENU
    sa23420 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23421 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa23422 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39225 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa44902 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-chd4a
    1
    CRISPR2-chd4a
    1
    MO1-chd4a N/A 1
    MO2-chd4a N/A 1
    MO3-chd4a N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH chd4a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Sifrim-Hitz-Weiss syndrome 617159
    DISEASE ASSOCIATED WITH chd4a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process fin regeneration (more)
    Cellular Component nucleus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chd4a-201 (1)    Ensembl 6394
    chd4a-202 (1)    Ensembl 472
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chd4a No data available
    MARKER RELATIONSHIPS
    chd4a Contained in: [BAC] CH211-51M24 (1)
    chd4a Encodes: [EST] IMAGE:7143343 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001044858 (1) 6394 nt
    Genomic GenBank:BX004850 (1) 121375 nt
    Select Tool
    Polypeptide UniProtKB:F1QWV5 (1) 1952 aa
    Sequence Information (all 20)
    ORTHOLOGY for chd4a ( Chr: 19 )
    CITATIONS (27)