Gene

chd4a

ID
ZDB-GENE-041111-187
Name
chromodomain helicase DNA binding protein 4a
Symbol
chd4a Nomenclature History
Previous Names
  • im:7143343
  • si:ch211-51m24.3
Type
protein_coding_gene
Location
Chr: 19 Mapping Details/Browsers
Description
Predicted to have several functions, including ATP binding activity; RNA polymerase II repressing transcription factor binding activity; and histone deacetylase binding activity. Involved in fin regeneration. Predicted to localize to NuRD complex. Is expressed in blastomere and central nervous system. Orthologous to human CHD4 (chromodomain helicase DNA binding protein 4).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
7 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With chd4a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Sifrim-Hitz-Weiss syndrome 617159
Associated With chd4a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
Conserved_site IPR019786 Zinc finger, PHD-type, conserved site
Conserved_site IPR023779 Chromo domain, conserved site
Domain IPR000330 SNF2-related domain
Domain IPR000953 Chromo/chromo shadow domain
Domain IPR001650 Helicase, C-terminal
Domain IPR001965 Zinc finger, PHD-type
Domain IPR009462 Domain of unknown function DUF1086
Domain IPR009463 Domain of unknown function DUF1087
Domain IPR012957 CHD, C-terminal 2
Domain IPR012958 CHD, N-terminal
Domain IPR014001 Helicase superfamily 1/2, ATP-binding domain
Domain IPR019787 Zinc finger, PHD-finger
Domain IPR023780 Chromo domain
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Homologous_superfamily IPR016197 Chromo-like domain superfamily
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR038718 SNF2-like, N-terminal domain superfamily
Domain Details Per Protein
Protein Length CHD, C-terminal 2 CHD, N-terminal Chromo/chromo shadow domain Chromo domain Chromo domain, conserved site Chromo-like domain superfamily DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site Domain of unknown function DUF1086 Domain of unknown function DUF1087 Helicase, C-terminal Helicase superfamily 1/2, ATP-binding domain P-loop containing nucleoside triphosphate hydrolase SNF2-like, N-terminal domain superfamily SNF2-related domain Zinc finger, FYVE/PHD-type Zinc finger, PHD-finger Zinc finger, PHD-type Zinc finger, PHD-type, conserved site Zinc finger, RING/FYVE/PHD-type
UniProtKB:Q1LYP4 1929
UniProtKB:F1QWV5 1952
UniProtKB:A4IG92 584
UniProtKB:I3ITG3 38
UniProtKB:A9JSS2 586
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations