Gene

fmnl2b

ID
ZDB-GENE-041111-182
Name
formin-like 2b
Symbol
fmnl2b Nomenclature History
Previous Names
  • fa31c06
  • im:7143207
  • wu:fa31c06
Type
protein_coding_gene
Location
Chr: 6 Mapping Details/Browsers
Description
Predicted to have actin filament binding activity. Predicted to be involved in cell migration; cortical actin cytoskeleton organization; and regulation of cell shape. Predicted to localize to cytosol. Is expressed in several structures, including hatching gland; heart tube; nervous system; optic cup; and solid lens vesicle. Orthologous to human FMNL2 (formin like 2).
Genome Resources
Note
None
Expression
All Expression Data
8 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With fmnl2b Human Ortholog
No data available
Associated With fmnl2b Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR010472 Formin, FH3 domain
Domain IPR010473 Formin, GTPase-binding domain
Domain IPR014767 Diaphanous autoregulatory (DAD) domain
Domain IPR014768 Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
Domain IPR015425 Formin, FH2 domain
Family IPR043592 Formin-like protein
Homologous_superfamily IPR016024 Armadillo-type fold
Homologous_superfamily IPR042201 Formin, FH2 domain superfamily
Domain Details Per Protein
Protein Length Armadillo-type fold Diaphanous autoregulatory (DAD) domain Formin, FH2 domain Formin, FH2 domain superfamily Formin, FH3 domain Formin, GTPase-binding domain Formin-like protein Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
UniProtKB:I3ITG0 462
UniProtKB:E7F0M4 1104
UniProtKB:A0A2R8QDH2 1129
UniProtKB:A0A2R8RYU9 1110
UniProtKB:I3ISF9 197
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Gene Tree
Ensembl
Citations