ZFIN ID: ZDB-GENE-041111-182
Gene Name: formin-like 2b
Gene Symbol: fmnl2b    Nomenclature History

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Previous Names: fa31c06, im:7143207, wu:fa31c06

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 6 Mapping Details/Browsers
Description: Predicted to have actin filament binding activity. Predicted to be involved in cell migration; cortical actin cytoskeleton organization; and regulation of cell shape. Predicted to localize to cytosol. Is expressed in several structures, including hatching gland; heart tube; nervous system; optic cup; and solid lens vesicle. Orthologous to human FMNL2 (formin like 2).
Genome Resources: Alliance (1),  Gene:492608 (1),  Ensembl(GRCz11):ENSDARG00000075041 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la025371Tg Transgenic Insertion Unknown Unknown DNA
sa13162 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-fmnl2b N/A 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH fmnl2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH fmnl2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process actin cytoskeleton organization (more)
    Cellular Component cytosol (more)
    Molecular Function actin binding (more)
    GO Terms (all 9)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA fmnl2b-202 (1)    Ensembl 609
    fmnl2b-203 (1)    Ensembl 2913
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM fmnl2b No data available
    MARKER RELATIONSHIPS
    fmnl2b Contained in: [BAC] CH73-377E7 (1)
    fmnl2b Encodes: [EST] fa31c06, IMAGE:7143207 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005165857 (1) 4870 nt
    Genomic GenBank:CR853290 (1) 196624 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QDH2 (1) 1129 aa
    Sequence Information (all 21)
    ORTHOLOGY for fmnl2b ( Chr: 6 )
    CITATIONS (23)