Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-041108-2
Gene Name: surfeit 1
Gene Symbol: surf1
Previous Names: im:6898613, zgc:158646
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Directly Submitted Expression Data: 1 figure (1 image) from Thisse et al., 2004 [IMAGE:6898613]
Wild-type Stages, Structures: Zygote:1-cell (0.0h-0.75h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
  unspecified, whole organism
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: la029083Tg
Knockdown reagents: MO1-surf1 (1)
PHENOTYPE
Data: 7 figures from Baden et al., 2007
Observed in: apoptotic process, cytochrome-c oxidase activity, digestive tract development, eye (all 17) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Leigh syndrome, due to COX deficiency 256000
GENE ONTOLOGY
Ontology GO Term
Biological Process embryonic organ development (more)
Cellular Component membrane (more)
Molecular Function cytochrome-c oxidase activity (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002994 (1)
  • PROSITE:PS50895 (1)
  • Pfam:PF02104 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA surf1-001 (1) 1128
    ncRNA surf1-002 (1) 818
    surf1-003 (1) 436
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM surf1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    surf1 Contained in: [BAC] CH73-278C20 (1) (order this), DKEY-226M8 (1)
    surf1 Encodes: [EST] IMAGE:6898613 (1) (order this)
    [cDNA] MGC:158646 (1) (order this), MGC:191437 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001080173 (1) 1044 bp
    Genomic GenBank:CR382323 143411 bp
    Select Tool
    Polypeptide UniProtKB:A1L248 (1) 309 aa
    Sequence Clusters UniGene:82799 (1)
    Sequence Information (all 20)
    OTHER surf1 GENE PAGES
  • Gene:557970 (1)
  • VEGA:OTTDARG00000023244 (1)
  • Ensembl(Zv9):ENSDARG00000003592 (1)
  • MAPPING INFORMATION
    Chr: 5 Details
    ORTHOLOGY
      Evidence
    Species Symbol Chromosome (Position) Accession # AA NT CL
    Zebrafish surf1 5  
    Human SURF1 9 (9q34.2)
  • OMIM:185620
  • Gene:6834
  • CITATIONS (18)